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ChemicalBook > Product Catalogue >API >Digestive system drugs >Gastric Acid Inhibitors >Ranitidine Hydrochloride

Ranitidine Hydrochloride

Ranitidine Hydrochloride Structure
  • ₹3300 - ₹10424.48
  • Product name: Ranitidine Hydrochloride
  • CAS: 66357-59-3
  • MF: C13H23ClN4O3S
  • MW: 350.86
  • EINECS:266-333-0
  • MDL Number:MFCD00941509
  • Synonyms:RANITIDINEHYDROCHLORIDE,USP;N'-[2-[[5-(dimethylaminomethyl)-2-furyl]methylsulfanyl]ethyl]-N-methyl-2-nitro-ethene-1,1-diamine;Azantac;Melfax;Raniben;Raniplex;Zintac;Ceototac
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberR0073
  • Product descriptionRanitidine Hydrochloride
  • Packaging5G
  • Price₹3300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0073
  • Product descriptionRanitidine Hydrochloride
  • Packaging25G
  • Price₹8700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR101
  • Product descriptionRanitidine hydrochloride solid
  • Packaging1G
  • Price₹3983.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1026
  • Product descriptionRanitidine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹10002.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR101
  • Product descriptionRanitidine hydrochloride solid
  • Packaging5G
  • Price₹10424.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0073 Ranitidine Hydrochloride 5G ₹3300 2022-05-26 Buy
TCI Chemicals (India) R0073 Ranitidine Hydrochloride 25G ₹8700 2022-05-26 Buy
Sigma-Aldrich(India) R101 Ranitidine hydrochloride solid 1G ₹3983.6 2022-06-14 Buy
Sigma-Aldrich(India) PHR1026 Ranitidine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹10002.3 2022-06-14 Buy
Sigma-Aldrich(India) R101 Ranitidine hydrochloride solid 5G ₹10424.48 2022-06-14 Buy

Properties

Melting point :134°C (dec.)
storage temp. :2-8°C
solubility :H2O: 1.8 mg/mL
form :solid
color :tan
Water Solubility :Soluble in water, 2-hydroxypropyl-beta-cyclodextrin, acetic acid, methanol, ethanol and dimethyl sulfoxide. Insoluble in chloroform.
Sensitive :Hygroscopic
Merck :14,8110
BCS Class :3/1
Stability :Hygroscopic
CAS DataBase Reference :66357-59-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Histamine H2 receptors mediate gastric acid secretion by coupling to Gαs proteins and increasing cAMP formation. Ranitidine is an antihistamine that antagonizes the histamine H2 receptor (pKi = 7.1) in gastric cells, which leads to a decrease in gastric acid secretion and a reduction of hydrogen ion concentration. Ranitidine inhibits intracellular cAMP production with an IC50 value of 1 μM. Its gastroprotective activity has been exploited for the treatment of various gastric acid disorders.

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Suppliers and manufacturers

AARTIA KEM SCIENCE Vivimed Labs Ltd Solara Active Pharma Sciences Ltd SMS Lifesciences India Ltd (MAHI Drugs Pvt Ltd) Orchev Pharma Pvt Ltd Saraca Laboratories Limited (Virchow Group) Anika International Pvt. Limited Vivimed Labs Ltd. SL Drugs & Pharmaceuticals Chempro Pharma Pvt. Ltd.