REVERSINE
|
- ₹7300 - ₹27300
- Product name: REVERSINE
- CAS: 656820-32-5
- MF: C21H27N7O
- MW: 393.49
- EINECS:
- MDL Number:MFCD07784513
- Synonyms:9H-Purine-2,6-diamine,N6-cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-;N6-Cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2,6-diamine;2-(4-MORPHOLINOANILINO)-6-CYCLOHEXYLAMINOPURINE;N6-CYCLOHEXYL-N2-(4-MORPHOLINOPHENYL)-9H-PURINE-2,6-DIAMINE;Picropodophyllin (PPP);N6-Cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-1H-purine-2,6-diamine Reversine;Reversine N6-Cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-1H-purine-2,6-diamine;REVERSINE
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberR3904
- Product descriptionReversine ≥98% (HPLC), solid
- Packaging1MG
- Price₹7300
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR3904
- Product descriptionReversine ≥98% (HPLC), solid
- Packaging5MG
- Price₹27300
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | R3904 | Reversine ≥98% (HPLC), solid | 1MG | ₹7300 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | R3904 | Reversine ≥98% (HPLC), solid | 5MG | ₹27300 | 2022-06-14 | Buy |
Properties
Melting point :305℃ (decomposition)
Boiling point :736.4±70.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 7 mg/mL, soluble
form :solid
pka :10.51±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
Boiling point :736.4±70.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 7 mg/mL, soluble
form :solid
pka :10.51±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Reversine is a cell-permeable, 2,6-disubstituted purine analog that acts as a dedifferentiation-inducing agent. Reversine is shown to induce mouse C2C12 myoblast cells to become multipotent mesenchymal progenitor cells in the concentration range of 1-10 M. Reversine is also the first organic molecule that has been demonstrated to reverse the cellular differentiation process. The compound acts as a selective A3 adenosine receptor antagonist (Ki= 660 nM, >10 M, and >10 M for hA3, hA1, and hA2A, respectively. Reversine functions as a dual inhibitor of MEK1 and nonmuscle myosin II heavy chain (IC50 = 8 and 10 nM, respectively). The compound also acts as an ATP-competitive, reversible and selective inhibitor of ARK-1, ARK-2, and ARK-3 (IC50 = 400, 500 and 400 nM, respectively) in a 26-kinase panel.More related product prices
Canertinib BMS-754807 871700-17-3 AVP-AEW541 MG-132 LY-2584702 (tosylate salt) Ginkgolide B Rimonabant CYCLOPAMINERelated product price
- AVP-AEW541
₹19247.4-77355.9 - MG-132
₹6600.01-40810 - LY-2584702 (tosylate salt)
₹47963.1
