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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Transmembrane Transporters >Sodium Channel Inhibitor >Rufinamide

Rufinamide

Rufinamide Structure
  • ₹2300 - ₹61962.3
  • Product name: Rufinamide
  • CAS: 106308-44-5
  • MF: C10H8F2N4O
  • MW: 238.19
  • EINECS:200-659-6
  • MDL Number:MFCD00865314
  • Synonyms:1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE, 1-[(2,6-DIFLUOROPHENYL)METHYL]-;Rufinamide;Rufinamide (200 mg);RufinaMide(Banzel);CGP 33101;E 2080;Inovelon;RUF 331
7 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 50MG
  • 100MG
  • 500MG
  • 1G
  • 1ML
  • ManufacturerTCI Chemicals (India)
  • Product numberR0143
  • Product descriptionRufinamide
  • Packaging25MG
  • Price₹2300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0143
  • Product descriptionRufinamide
  • Packaging100MG
  • Price₹5700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0143
  • Product descriptionRufinamide
  • Packaging1G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR8404
  • Product descriptionRufinamide ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹13780.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1625
  • Product descriptionRufinamide Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹16540.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR-023
  • Product descriptionRufinamide solution 1.0?mg/mL in acetonitrile: water (9:1), certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹18300.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR8404
  • Product descriptionRufinamide ≥98% (HPLC), powder
  • Packaging50MG
  • Price₹61962.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0143 Rufinamide 25MG ₹2300 2022-05-26 Buy
TCI Chemicals (India) R0143 Rufinamide 100MG ₹5700 2022-05-26 Buy
TCI Chemicals (India) R0143 Rufinamide 1G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) R8404 Rufinamide ≥98% (HPLC), powder 10MG ₹13780.23 2022-06-14 Buy
Sigma-Aldrich(India) PHR1625 Rufinamide Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹16540.6 2022-06-14 Buy
Sigma-Aldrich(India) R-023 Rufinamide solution 1.0?mg/mL in acetonitrile: water (9:1), certified reference material, Cerilliant? 1ML ₹18300.8 2022-06-14 Buy
Sigma-Aldrich(India) R8404 Rufinamide ≥98% (HPLC), powder 50MG ₹61962.3 2022-06-14 Buy

Properties

Melting point :232-234?C
Boiling point :473.8±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :-20°C
solubility :DMSO: soluble9mg/mL
pka :14.37±0.50(Predicted)
form :powder
color :white
Merck :14,8293
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Lennox-Gastaut syndrome (LGS) is a severe pediatric epilepsy syndrome characterized by multiple seizure types. Rufinamide is a triazole derivative that serves as the active ingredient in a formulation that is used in adjunctive treatment of LGS to limit seizure frequency. The mechanism of action of rufinamide is unclear, although it is thought to limit the frequency of sodium-dependent neuronal action potentials.

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