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ST638

ST638 Structure
  • ₹23663.45
  • Product name: ST638
  • CAS: 107761-24-0
  • MF: C19H18N2O3S
  • MW: 354.42
  • EINECS:
  • MDL Number:MFCD00236446
  • Synonyms:ST638;TYRPHOSTIN ST 638;2-cyano-3-(3-ethoxy-4-hydroxy-5-((phenylthio)methyl)phenyl)-2-propenamid ;2-cyano-3-(3-ethoxy-4-hydroxy-5-((phenylthio)methyl)phenyl)-2-propenamide ;ALPHA-CYANO-(3-ETHOXY-4-HYDROXY-5-PHENYLTHIOMETHYL)CINNAMIDE;α-cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide;2-Cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl]propenamide;2-Propenamide, 2-cyano-3-[3-ethoxy-4-hydroxy-5-[(phenylthio)methyl]phenyl]-
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberS1195
  • Product descriptionST638 ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹23663.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S1195 ST638 ≥98% (HPLC), solid 5MG ₹23663.45 2022-06-14 Buy

Properties

Melting point :134-135.5 °C
Boiling point :611.2±55.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: 19 mg/mL
pka :8.79±0.50(Predicted)
form :solid
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

ST638 is a tyrosine kinase inhibitor (IC50 = 370 nM). It suppresses tyrosine phosphorylation induced by tumor necrosis factor-α and phorbol myristate acetate in neutrophils and by angiotensin II in cardiac fibroblasts.

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