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STIRIPENTOL

STIRIPENTOL Structure
  • ₹8822.38 - ₹35744.15
  • Product name: STIRIPENTOL
  • CAS: 49763-96-4
  • MF: C14H18O3
  • MW: 234.29
  • EINECS:256-480-9
  • MDL Number:MFCD00869310
  • Synonyms:(RS)-(E)-4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol;1-(1,3-BENZODIOXOL-5YL)-4,4-DIMETHYL-1-PENTEN-3-OL;STIRIPENTOL;1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-o ;4,4-dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-o ;4,4-dimethyl-1-(3,4-methylenedioxyphenyl)-1-penten-3-ol ;bcx2600 ;1-(Benzo[d][1,3]dioxol-5-yl)-4,4-dimethylpent-1-en-3-ol
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberS0905
  • Product descriptionStiripentol min. 98.0 %
  • Packaging1G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberS0905
  • Product descriptionStiripentol min. 98.0 %
  • Packaging5G
  • Price₹34300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS6826
  • Product descriptionStiripentol ≥98% (HPLC)
  • Packaging5MG
  • Price₹8822.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS6826
  • Product descriptionStiripentol ≥98% (HPLC)
  • Packaging25MG
  • Price₹35744.15
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) S0905 Stiripentol min. 98.0 % 1G ₹9800 2022-05-26 Buy
TCI Chemicals (India) S0905 Stiripentol min. 98.0 % 5G ₹34300 2022-05-26 Buy
Sigma-Aldrich(India) S6826 Stiripentol ≥98% (HPLC) 5MG ₹8822.38 2022-06-14 Buy
Sigma-Aldrich(India) S6826 Stiripentol ≥98% (HPLC) 25MG ₹35744.15 2022-06-14 Buy

Properties

Melting point :73-74°C
Boiling point :365.4±11.0 °C(Predicted)
Density :1.139±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: ≥20mg/mL
pka :14.45±0.20(Predicted)
form :powder
color :white to beige
InChIKey :IBLNKMRFIPWSOY-FNORWQNLSA-N
CAS DataBase Reference :49763-96-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Stiripentol is a third-generation anti-epileptic drug that is known to inhibit the synaptosomal uptake of GABA, increasing the activation of GABAA receptors. It also inhibits microsomal cytochrome P450 (CYP) isoforms CYP3A4, CYP1A2, and CYP2C19. More recently, stiripentol and analogs have been shown to inhibit lactate dehydrogenase (LDH), blocking both lactate to pyruvate and pyruvate to lactate conversions by human LDH isoforms 1 and 5 at 500 μM. In this way, stiripentol mimics ketogenic diets, which can also lower lactate levels in the brain and prevent seizures.

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