Tadalafil
- ₹7934.73 - ₹26748.58
- Product name: Tadalafil
- CAS: 171596-29-5
- MF: C22H19N3O4
- MW: 389.4
- EINECS:687-782-2
- MDL Number:MFCD07771966
- Synonyms:ICOS 351;UK 336017;TADALAFIL(CIALIS);Taladafil (cialis);Cialis/taladafil;(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;Cialis ,98%;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-
5 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 20MG
- 50MG
- 500MG
- 1ML
- ManufacturerSigma-Aldrich(India)
- Product numberSML1877
- Product descriptionTadalafil ≥98% (HPLC)
- Packaging50MG
- Price₹26748.58
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberNMID941
- Product descriptionTadalafil
- Packaging20MG
- Price₹25536.18
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT-072
- Product descriptionTadalafil solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹16837.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1810
- Product descriptionTadalafil Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging500MG
- Price₹16215.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1877
- Product descriptionTadalafil ≥98% (HPLC)
- Packaging10MG
- Price₹7934.73
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML1877 | Tadalafil ≥98% (HPLC) | 50MG | ₹26748.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | NMID941 | Tadalafil | 20MG | ₹25536.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T-072 | Tadalafil solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹16837.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1810 | Tadalafil Pharmaceutical Secondary Standard; Certified Reference Material | 500MG | ₹16215.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1877 | Tadalafil ≥98% (HPLC) | 10MG | ₹7934.73 | 2022-06-14 | Buy |
Properties
Melting point :298-300°C
alpha :D20 +71.0°
Boiling point :679.1±55.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :16.68±0.40(Predicted)
color :white to beige
optical activity :[α]/D +68 to +78°, c = 1 in chloroform-d
BCS Class :4
Stability :Unstable in Methanol
InChI :InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
InChIKey :WOXKDUGGOYFFRN-IIBYNOLFSA-N
SMILES :N1C2=C(C=CC=C2)C2C[C@]3([H])C(=O)N(C)CC(=O)N3[C@H](C3=CC=C4OCOC4=C3)C1=2
CAS DataBase Reference :171596-29-5(CAS DataBase Reference)
alpha :D20 +71.0°
Boiling point :679.1±55.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
Flash point :2℃
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :16.68±0.40(Predicted)
color :white to beige
optical activity :[α]/D +68 to +78°, c = 1 in chloroform-d
BCS Class :4
Stability :Unstable in Methanol
InChI :InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
InChIKey :WOXKDUGGOYFFRN-IIBYNOLFSA-N
SMILES :N1C2=C(C=CC=C2)C2C[C@]3([H])C(=O)N(C)CC(=O)N3[C@H](C3=CC=C4OCOC4=C3)C1=2
CAS DataBase Reference :171596-29-5(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Tadalafil (market name “Cialis” or “Adcirca”) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. The mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia.More related product prices
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