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TYRPHOSTIN RG 13022

TYRPHOSTIN RG 13022 Structure
  • ₹8700 - ₹26000
  • Product name: TYRPHOSTIN RG 13022
  • CAS: 136831-48-6
  • MF: C16H14N2O2
  • MW: 266.29
  • EINECS:
  • MDL Number:MFCD00236444
  • Synonyms:3-(3,4-Dimethoxyphenyl)-2-(3-pyridinyl)propenenitrile;α-(3-Pyridyl)-3,4-dimethoxybenzeneacrylonitrile;3-(3,4-dimethoxyphenyl)-2-(pyridin-3-yl)acrylonitrile;3-Pyridineacetonitrile,a-[(3,4-dimethoxyphenyl)methylene]-;ALPHA-(3'-PYRIDYL)-(3,4-DIMETHOXY)CINNAMONITRILE;RG-13022;TYRPHOSTIN RG 13022;2-(3,4'-DIMETHOXYPHENYL)-1-(3''-PYRIDINYL)ACRYLONITRILE
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberT3575
  • Product descriptionTyrphostin RG 13022 min. 98.0 %
  • Packaging25MG
  • Price₹8700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3575
  • Product descriptionTyrphostin RG 13022 min. 98.0 %
  • Packaging100MG
  • Price₹26000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T3575 Tyrphostin RG 13022 min. 98.0 % 25MG ₹8700 2022-05-26 Buy
TCI Chemicals (India) T3575 Tyrphostin RG 13022 min. 98.0 % 100MG ₹26000 2022-05-26 Buy

Properties

Melting point :116.0 to 120.0 °C
Boiling point :423.8±45.0 °C(Predicted)
Density :1.172±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO or ethanol: soluble
pka :3.03±0.12(Predicted)
form :White solid.
color :White to Yellow to Green

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

RG-13022 is a Tyrosine kinase tyrphostin. Reports indicate that RG-13022 suppresses epidermal growth factor (EGF)-stimulated cancer cell proliferation in cancer cell studies. Additionally, RG-13022 has been described to inhibit EGF, platelet-dervied growth (PDGF) signaling, and PDGF enhanced DNA synthesis. RG-13022 is an inhibitor of EGFR and PDGFR.

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