ZPCK
- ₹12686.9
- Product name: ZPCK
- CAS: 26049-94-5
- MF: C18H18ClNO3
- MW: 331.79
- EINECS:247-432-8
- MDL Number:MFCD00037114
- Synonyms:SL-01;carbamicacid,[3-chloro-2-oxo-1-(phenylmethyl)propyl]-,phenylmethylester,(s ;(S)-benzyl [1-benzyl-3-chloro-2-oxopropyl]carbamate;N-CBZ-L-PHENYLALANINE CHLOROMETHYL*KETON E;z-l-phe chloromethyl ketone;(S)-Penzyl [1-benzyl-3-chloro-2-oxopropyl]carbamate.;ZPCK, N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone;(3S)-1-Chloro-3-(benzyloxycarbonylamino)-4-phenyl-2-butanone
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1G
- ManufacturerSigma-Aldrich(India)
- Product number860794
- Product descriptionZ-L-Phe chloromethyl ketone 98%
- Packaging1G
- Price₹12686.9
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 860794 | Z-L-Phe chloromethyl ketone 98% | 1G | ₹12686.9 | 2022-06-14 | Buy |
Properties
Melting point :107-108 °C(lit.)
Boiling point :503.1±50.0 °C(Predicted)
Density :1.1630 (rough estimate)
refractive index :1.6470 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
form :solid
pka :10.74±0.46(Predicted)
color :White
optical activity :[α]23/D +30°, c = 1 in chloroform
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :26049-94-5
EPA Substance Registry System :Benzyl [(1S)-3-chloro-2-oxo-1-benzylpropyl]carbamate (26049-94-5)
Boiling point :503.1±50.0 °C(Predicted)
Density :1.1630 (rough estimate)
refractive index :1.6470 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
form :solid
pka :10.74±0.46(Predicted)
color :White
optical activity :[α]23/D +30°, c = 1 in chloroform
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :26049-94-5
EPA Substance Registry System :Benzyl [(1S)-3-chloro-2-oxo-1-benzylpropyl]carbamate (26049-94-5)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
SL 01 is a prodrug of gemcitabine , the nucleoside analog used intravenously to treat various cancers that was designed for improved oral bioavailability. SL 01 can inhibit the growth of human non-small cell lung cancer NCI-H460 cells, colon cancer HCT-116 cells, and breast cancer MCF-7 cells (IC50s = 0.78, 0.92, and 0.64 μM, respectively), inducing apoptosis. In nude mice bearing NCI-H460, HCT-116, or MCF-7 cancer cell xenografts, SL 01 at 10-50 μM/kg has been shown to delay tumor growth.More related product prices
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