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ChemicalBook >> CAS DataBase List >> 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE

4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE price.
  • $39 - $2230
  • Product name: 4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE
  • CAS: 191219-80-4
  • MF: C17H16ClN3O
  • MW: 313.78
  • EINECS:
  • MDL Number:MFCD04113219
  • Synonyms:YM 976;4-(3-CHLOROPHENYL)-1,7-DIETHYLPYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE;4-(3-Chloro-phenyl)-1,7-diethyl-1H-pyrido[2,3-d]pyrimidin-2-one;Pyrido[2,3-d]pyrimidin-2(1H)-one, 4-(3-chlorophenyl)-1,7-diethyl-;YM-976,Phosphodiesterase (PDE),PDE4 inhibitor,inhibit,phosphodiesterase 4,anti-inflammatory activities,antigen-induced airway responses,Inhibitor,YM976,YM 976
Price28 Properties Safety Information Description
28 prices
Selected condition：
Brand
  • Activate Scientific
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Crysdot
  • CSNpharm
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerActivate Scientific
  • Product numberAS148423
  • Product descriptionYM 976 97%
  • Packaging100mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0056CQ
  • Product description4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
  • Packaging1mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number191219804
  • Product description4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
  • Packaging1g
  • Price$828.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging1mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging10mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging50mg
  • Price$151
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging100mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging250mg
  • Price$521
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA566146
  • Product descriptionYM 976 97%
  • Packaging1g
  • Price$2219
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008421
  • Product descriptionYM 976 95.00%
  • Packaging10MG
  • Price$673.08
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008421
  • Product descriptionYM 976 95.00%
  • Packaging50MG
  • Price$1102.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008421
  • Product descriptionYM 976 95.00%
  • Packaging1G
  • Price$1529.85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6870
  • Product descriptionYM 976
  • Packaging10mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6870
  • Product descriptionYM 976
  • Packaging50mg
  • Price$959
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29529
  • Product descriptionYM 976
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS148423 YM 976 97% 100mg $375 2021-12-16 Buy
AK Scientific 0056CQ 4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one 1mg $112 2021-12-16 Buy
Alichem 191219804 4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one 1g $828.1 2021-12-16 Buy
Ambeed A566146 YM 976 97% 1mg $39 2021-12-16 Buy
Ambeed A566146 YM 976 97% 5mg $66 2021-12-16 Buy
Ambeed A566146 YM 976 97% 10mg $86 2021-12-16 Buy
Ambeed A566146 YM 976 97% 50mg $151 2021-12-16 Buy
Ambeed A566146 YM 976 97% 100mg $268 2021-12-16 Buy
Ambeed A566146 YM 976 97% 250mg $521 2021-12-16 Buy
Ambeed A566146 YM 976 97% 1g $2219 2021-12-16 Buy
American Custom Chemicals Corporation API0008421 YM 976 95.00% 10MG $673.08 2021-12-16 Buy
American Custom Chemicals Corporation API0008421 YM 976 95.00% 50MG $1102.4 2021-12-16 Buy
American Custom Chemicals Corporation API0008421 YM 976 95.00% 1G $1529.85 2021-12-16 Buy
ApexBio Technology B6870 YM 976 10mg $234 2021-12-16 Buy
ApexBio Technology B6870 YM 976 50mg $959 2021-12-16 Buy
Cayman Chemical 29529 YM 976 5mg $93 2024-03-01 Buy
Next Last

Properties

Melting point :132.7-134.0 °C(lit.)
Boiling point :485.4±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 16 mg/mL
form :solid
pka :2.11±0.20(Predicted)
color :pale yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

YM 976 is an inhibitor of PDE4 (phosphodiesterase 4) (IC50 = 2.2 nM), which is an enzyme responsible for hydrolyzing cyclic phosphodiesters in the secondary messenger molecule cAMP. This allows the secondary messenger to have a longer half life and thus increases the length and intensity of signal transduction.

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