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ChemicalBook >> CAS DataBase List >> PF 04995274

PF 04995274

PF 04995274 price.
  • $34 - $2450
  • Product name: PF 04995274
  • CAS: 1331782-27-4
  • MF: C23H32N2O6
  • MW: 432.51
  • EINECS:
  • MDL Number:
  • Synonyms:PF 04995274;PF-04995274 >=98% (HPLC);2H-Pyran-4-ol, tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-;PF04995274;PF 04995274;4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol;Inhibitor,5-HT4,5-hydroxytryptamine Receptor,behavior,Alzheimer′s disease,PF-04995274,inhibit,PF04995274,Serotonin Receptor,5-HT Receptor,Stress-induced,PF 04995274,depressive-like;(R)-4-((4-(((4-((Tetrahydrofuran-3-yl)oxy)benzo[d]isoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol
14 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number6654DK
  • Product descriptionPF-04995274
  • Packaging1mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number6654DK
  • Product descriptionPF-04995274
  • Packaging10mg
  • Price$301
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28776
  • Product descriptionPF-04995274
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28776
  • Product descriptionPF-04995274
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28776
  • Product descriptionPF-04995274
  • Packaging10mg
  • Price$183
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28776
  • Product descriptionPF-04995274
  • Packaging25mg
  • Price$412
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007316
  • Product descriptionPF-04995274 99.42%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007316
  • Product descriptionPF-04995274 99.42%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007316
  • Product descriptionPF-04995274 99.42%
  • Packaging25mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007316
  • Product descriptionPF-04995274 99.42%
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007316
  • Product descriptionPF-04995274 99.42%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9915
  • Product descriptionPF-04995274 >98%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9915
  • Product descriptionPF-04995274 >98%
  • Packaging250mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9915
  • Product descriptionPF-04995274 >98%
  • Packaging1g
  • Price$2450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6654DK PF-04995274 1mg $136 2021-12-16 Buy
AK Scientific 6654DK PF-04995274 10mg $301 2021-12-16 Buy
Cayman Chemical 28776 PF-04995274 1mg $34 2024-03-01 Buy
Cayman Chemical 28776 PF-04995274 5mg $100 2024-03-01 Buy
Cayman Chemical 28776 PF-04995274 10mg $183 2024-03-01 Buy
Cayman Chemical 28776 PF-04995274 25mg $412 2024-03-01 Buy
ChemScene CS-0007316 PF-04995274 99.42% 5mg $80 2021-12-16 Buy
ChemScene CS-0007316 PF-04995274 99.42% 10mg $150 2021-12-16 Buy
ChemScene CS-0007316 PF-04995274 99.42% 25mg $250 2021-12-16 Buy
ChemScene CS-0007316 PF-04995274 99.42% 50mg $450 2021-12-16 Buy
ChemScene CS-0007316 PF-04995274 99.42% 100mg $650 2021-12-16 Buy
DC Chemicals DC9915 PF-04995274 >98% 100mg $650 2021-12-16 Buy
DC Chemicals DC9915 PF-04995274 >98% 250mg $1200 2021-12-16 Buy
DC Chemicals DC9915 PF-04995274 >98% 1g $2450 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:20.0(Max Conc. mg/mL);46.2(Max Conc. mM)
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PF-04995274 is a partial agonist of the serotonin (5-HT) receptor subtypes 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E (Kis = 0.36, 0.46, 0.15, and 0.32 nM, respectively, in a radioligand binding assay). It increases cAMP levels in HEK293 cells expressing 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E receptors (EC50s = 0.47, 0.36, 0.37, and 0.26 nM, respectively, for the human recombinant receptors). PF-04995274 decreases scopolamine-induced increases in the distance traveled in the Morris water maze in rats when administered at a dose of 0.032 mg/kg.