2-METHYL-4'-(TRIFLUOROMETHYL)-1,1'-BIPHENYL synthesis

10synthesis methods

Product Name:2-METHYL-4'-(TRIFLUOROMETHYL)-1,1'-BIPHENYL
CAS Number:167021-49-0
Molecular formula:C14H11F3
Molecular Weight:236.23

402-43-7 Synthesis

402-43-7
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16419-60-6 Synthesis

16419-60-6
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2-METHYL-4'-(TRIFLUOROMETHYL)-1,1'-BIPHENYL

167021-49-0
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Yield:167021-49-0 99%

Reaction Conditions:

with potassium phosphate;[5-(3-butylbenzimidazol-2-yliden-1-yl)-25,26,27,28-tetrapropyloxy calix[4]arene] (pyridine) palladium(II) dibromide in 1,4-dioxane at 100; for 24 h;Inert atmosphere;

Steps:

4.2.6 General procedure for Pd-catalysed Suzuki-Miyaura coupling

General procedure: In air, potassium phosphate (3mmol, 0.636g), catalyst 1 (0.08mol%, 0.0009g) and arylboronic acid (2mmol) were weighed into a 50mL glass vial that was sealed with a septum and purged with N₂ (3×). Dioxane (1mL) was then injected via syringe followed by the aryl bromide (1mmol) (if liquid). If the aryl bromide was a solid, it was introduced into the vial prior to purging with N₂. At this time, the reaction stirred for 24h at 100°C. The reaction mixture was concentrated in vacuo and directly purified via silica gel flash chromatography.

References:

Ren, Hui;Xu, Yong;Jeanneau, Erwann;Bonnamour, Isabelle;Tu, Tao;Darbost, Ulrich [Tetrahedron,2014,vol. 70,# 17,p. 2829 - 2837]

16419-60-6 Synthesis

16419-60-6
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$9.00/1g

98-56-6 Synthesis