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ChemicalBook CAS DataBase List 3-Bromo-1-fluoronaphthalene

3-Bromo-1-fluoronaphthalene synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sec-butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C
1.2: 92 percent / bromine / tetrahydrofuran; hexane
2.1: 89 percent / 2,2,6,6-tetramethylpiperidine; butyllithium / tetrahydrofuran; hexane / 6 h / -75 °C

References:

Leroux, Frederic;Mangano, Giuseppe;Schlosser, Manfred [European Journal of Organic Chemistry,2005,# 23,p. 5049 - 5054]

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