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ChemicalBook CAS DataBase List 4-(Trifluoromethyl)pyridine

4-(Trifluoromethyl)pyridine synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 90 percent / O3 / CH2Cl2; methanol / 24 h / -78 °C
2: 70 percent / NH3 / methanol / 24 h / Heating

References:

Jiang, Biao;Xiong, Xen-Nan;Yang, Cai-Guang [Bioorganic and Medicinal Chemistry Letters,2001,vol. 11,# 4,p. 475 - 477]

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