5-BROMO-2-(2-METHYL-2H-TETRAZOL-5-YL)-PYRIDINE synthesis
- Product Name:5-BROMO-2-(2-METHYL-2H-TETRAZOL-5-YL)-PYRIDINE
- CAS Number:380380-64-3
- Molecular formula:C7H6BrN5
- Molecular Weight:240.06
380380-60-9
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50-00-0
845 suppliers
$10.00/25g
380380-64-3
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$10.00/250mg
Yield:380380-64-3 90.4%
Reaction Conditions:
with palladium 10% on activated carbon;hydrogen in methanol at 20; under 1500.15 Torr; for 3 h;
Steps:
1 Preparation of 2-methyl-5- (5-bromopyridin-2-yl) tetrazole
1.5 L of methanol,5-bromo-2- (2H-tetrazol-5-yl) pyridine (226 g)Formaldehyde (90g),10% palladium on carbon (20 g) was added to the reactor,Under a hydrogen atmosphere (0.2 MPa)Stirred at room temperature for 3 hours, the reaction was completed,Organic phase evaporated,Recrystallization from acetonitrile,To give the product 2-methyl-5- (5-bromo-2-yl) tetrazolium,217 g, yield: 90.4%.
References:
CN106632240,2017,A Location in patent:Paragraph 0018-0019
380380-60-9
118 suppliers
$43.00/250mg
74-88-4
342 suppliers
$15.00/10g
380380-64-3
247 suppliers
$10.00/250mg
74-88-4
342 suppliers
$15.00/10g
380380-60-9
118 suppliers
$43.00/250mg
380380-64-3
247 suppliers
$10.00/250mg
380380-63-2
65 suppliers
$260.00/100mg
97483-77-7
549 suppliers
$10.00/5g
380380-64-3
247 suppliers
$10.00/250mg
380380-63-2
65 suppliers
$260.00/100mg
624-28-2
713 suppliers
$5.00/5g
380380-64-3
247 suppliers
$10.00/250mg