ChemicalBook CAS DataBase List METHYL 2-METHYL-4-HYDROXY-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXYLATE-1,1-DIOXIDE

METHYL 2-METHYL-4-HYDROXY-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXYLATE-1,1-DIOXIDE synthesis

9synthesis methods

Product Name:METHYL 2-METHYL-4-HYDROXY-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXYLATE-1,1-DIOXIDE
CAS Number:59804-25-0
Molecular formula:C9H9NO5S2
Molecular Weight:275.3

METHYL 4-HYDROXY-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXYLATE-1,1-DIOXIDE

98827-44-2
75 suppliers
$126.00/500mg

77-78-1
289 suppliers
$19.69/1ml

METHYL 2-METHYL-4-HYDROXY-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXYLATE-1,1-DIOXIDE

59804-25-0
127 suppliers
$250.00/250mg

Yield: 86%

Reaction Conditions:

with sodium hydroxide in methanol at 20; for 3 h;Concentration;

Steps:

1.3 3. methyl 4-hydroxy-2-methyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxylate-1,1-dioxide
5.3 g of TNXK-3 and 20 ml of methanol were added to a reaction flask. Stir at room temperature. Separately add dimethyl sulfate 3.7 g methanol (5 ml) solution and 50% sodium hydroxide solution (5 ml). After the completion of the dropping, room temperature reaction 3 hours, cooling to 10 degrees, the water 50 ml dilution, use 10% hydrochloric acid to the PH is 3. Filtering, the filter cake after the water washing, drying, recrystallization with methanol, 60 degrees decompression drying, getting white solid 4.8 g, yield 86%.

References:

Jiangxi Yong Tong Technology Co., Ltd.;Liu Zhongchun CN107141308, 2017, A Location in patent:Paragraph 0051-0055; 0065; 0069; 0075; 0079; 0085; 0089