5-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER synthesis

3synthesis methods

Product Name:5-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
CAS Number:865887-16-7
Molecular formula:C11H12N2O3
Molecular Weight:220.22

2H-Indazole-3-carboxylic acid, 5-methoxy-2-[[2-(trimethylsilyl)ethoxy]methyl]-, ethyl ester

1210745-27-9
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5-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

865887-16-7
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Yield:865887-16-7 79%

Reaction Conditions:

Stage #1: ethyl 5-methoxy-2-{[(2-trimethylsilyl)ethoxy]methyl}-2H-indazole-3-carboxylatewith hydrogenchloride;water in ethanol at 20;
Stage #2: with sodium carbonate in ethanol;water;

References:

Vernekar, Sanjeev Kumar V.;Hallaq, Hasan Y.;Clarkson, Guy;Thompson, Andrew J.;Silvestr, Linda;Lummis, Sarah C. R.;Lochner, Martin [Journal of Medicinal Chemistry,2010,vol. 53,# 5,p. 2324 - 2328] Location in patent:supporting information; experimental part

64-17-5 Synthesis

64-17-5
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90417-53-1 Synthesis

90417-53-1
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$54.00/100mg

865887-16-7
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References

39755-95-8 Synthesis

39755-95-8
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$8.00/1g

865887-16-7
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References

5-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER Related Search:

METHYL 5-METHOXY-1H-INDAZOLE-3-CARBOXYLATE 5-METHOXY-1H-INDAZOLE 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER 5-HYDROXY-1H-INDAZOLE-3-CARBOXALDEHYDE 1H-Indazol-5-ol 1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER 5-Methoxy-3-indazolecarboxylic acid