ethyl 3 - hydroxy - 4 - Methoxybenzoate synthesis
- Product Name:ethyl 3 - hydroxy - 4 - Methoxybenzoate
- CAS Number:148527-38-2
- Molecular formula:C10H12O4
- Molecular Weight:196.2
64-17-5
707 suppliers
$10.00/50g
645-08-9
326 suppliers
$10.00/1g
148527-38-2
22 suppliers
$353.00/5g
Yield:148527-38-2 95%
Reaction Conditions:
with sulfuric acid for 8 h;Reflux;
Steps:
Ethyl-3-hydroxy-4-methoxybenzoate (3a)
A mixture of 2 (0.84 g, 5 mmol) and concentrated H2SO4 (0.5 mL) inanhydrous ethanol (20 mL) was stirred at reflux for 8 h. The solvent was evaporated in vacuo, and the resulting residue wasextracted with EtOAc. The organic layer was washed with saturated NaHCO3 and water, dried over Na2SO4, and evaporatedto afford 3a (0.93 g, 95%).
References:
Shan, Yuanyuan;Lei, Jine;Zhang, Li;Fan, Te;Wang, Maoyi;Ma, Ying [Chemistry of Natural Compounds,2015,vol. 51,# 4,p. 620 - 625][Khim. Prir. Soedin.,2015,vol. 51,# 4,p. 536 - 540,5]
3943-89-3
414 suppliers
$6.00/5g
74-88-4
340 suppliers
$15.00/10g
148527-38-2
22 suppliers
$353.00/5g
621-59-0
617 suppliers
$9.00/1g
64-17-5
707 suppliers
$10.00/50g
148527-38-2
22 suppliers
$353.00/5g
621-59-0
617 suppliers
$9.00/1g
148527-38-2
22 suppliers
$353.00/5g