![](/CAS/GIF/138786-67-1.gif)
Pantoprazole Sodium synthesis
- Product Name:Pantoprazole Sodium
- CAS Number:138786-67-1
- Molecular formula:C16H14F2N3NaO4S
- Molecular Weight:405.35
![Pantoprazole](/CAS/GIF/102625-70-7.gif)
102625-70-7
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$28.00/250mg
![Pantoprazole Sodium](/CAS/GIF/138786-67-1.gif)
138786-67-1
453 suppliers
$19.80/5mg
Yield:138786-67-1 95%
Reaction Conditions:
with sodium hydroxide in water;acetonitrile at 20;
Steps:
14 Example 14
Pantoprazole (5 g, 25.6 mmol) and 47% NaOH (1 eq.) are added to acetonitrile (25ml) and stirred at room temperature. After 3 h, the mixture becomes clear, and crystals beginto form. The mixture is allowed to stand overnight. The crystals are filtered and dried at50°C under 10 mm Hg vacuum. The crystals are determined to be the sesquihydrate form ofpantoprazole sodium by PXRD and are found to have a water content of 7.0% by Karl Fisheranalysis. Yield: 95%.
References:
WO2004/111029,2004,A2 Location in patent:Page 24
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102625-64-9
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$11.00/5g
![Pantoprazole Sodium](/CAS/GIF/138786-67-1.gif)
138786-67-1
453 suppliers
$19.80/5mg
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409098-86-8
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![Pantoprazole Sodium](/CAS/GIF/138786-67-1.gif)
138786-67-1
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97963-62-7
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$7.00/5g
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72830-09-2
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$15.69/1g
![Pantoprazole Sodium](/CAS/GIF/138786-67-1.gif)
138786-67-1
453 suppliers
$19.80/5mg
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368890-20-4
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$330.00/1g
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124-41-4
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$12.00/25g
![Pantoprazole Sodium](/CAS/GIF/138786-67-1.gif)
138786-67-1
453 suppliers
$19.80/5mg