Repotrectinib: A New Anti-cancer Drug
Repotrectinib is an oral inhibitor of ROS1, and it represents the first approved targeted therapy that specifically includes patients previously treated with a ROS1 TKI in FDA labeling.
Sep 29，2025 API
Physical Properties and Potential Toxicity of Diethylene Glycol Dibutyl Ether in Industrial Applications
Explores DEGDBE's solvent properties, polyurethane applications, density data, and related toxicity concerns in industrial use.
Sep 29，2025 Organic Chemistry
The application of 4-methoxyphenylboronic acid in organic synthesis
4-Methoxyphenylboronic acid can be used as a organic reagent in Suzuki coupling reaction. This paper mainly reports the its application in organic synthesis
Sep 29，2025 Organic Synthesis Intermediate
Crystal structure and THz-TDS investigation of gallic acid monohydrate
Gallic acid monohydrate exhibits antibacterial and antiviral activities, its dehydration dynamic, crystal structure and THz-TDS investigation were reported.
Sep 28，2025 Supplements
Fmoc-Glu(OtBu)-OH: Self-Assembly, Drug Delivery, and Supramolecular Hydrogel Applications
Highlights Fmoc-Glu(OtBu)-OH's self-assembled nanostructures, targeted anticancer prodrug potential, and catalytic supramolecular hydrogel transformations.
Sep 28，2025 Organic Chemistry
A Comprehensive Analysis of Magnolol
This work details magnolol's diverse bioactivities, glucuronidation metabolism, solubility/bioavailability solutions, and safe use via toxicological studies.
Sep 26，2025 API
Multifunctional Roles of Polydeoxyribonucleotide in Tissue Regeneration and Repair
Polydeoxyribonucleotide enhances collagen synthesis, angiogenesis, wound repair, and osteoblast growth via A2A receptor activation.
Sep 26，2025 Nucleoside Drugs
2,4-Dichlorobenzoic Acid: Sources, Decomposition, Toxicology and Biodegradation
The article covers 2,4-Dichlorobenzoic acid's sources, decomposition, toxicology, and bacterial biodegradation, with structural confirmations.
Sep 26，2025 Chemical Reagents
2,3,4-Trimethoxybenzaldehyde: Properties and Anti-Candida Activity
2,3,4-Trimethoxybenzaldehyde (synthesis intermediate) inhibits Candida albicans planktonic growth (MIC 1mg/mL, MFC 2mg/mL) and yeast-hyphal transition.
Sep 26，2025 Chemical Materials
Application examples of 4-Nitrophthalonitrile
4-Nitrophthalonitrile is an efficient, low toxicity, broad-spectrum pesticide intermediate, of which application were reported here.
Sep 26，2025 Organic Synthesis Intermediate