H-89 DIHYDROCHLORIDE HYDRATE
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- CAS-Nr.
- 130964-39-5
- Englisch Name:
- H-89 DIHYDROCHLORIDE HYDRATE
- Synonyma:
- H 89 2HCl;5-Isoquinolinesulfonamide;H-89 DIHYDROCHLORIDE HYDRATE;H-89 hydrate dihydrochloride;H-89 DIHYDROCHLORIDE HYDRATE USP/EP/BP;Protein kinase inhibitor H-89 dihydrochloride;H-89 Dihydrochloride Hydrate,N-[2-(P-Bromocinnamylamino)Et;H-89 dihydrochloride(Protein kinase inhibitor H-89 dihydrochloride);PROTEIN KINASE INHIBITOR H-89 DIHYDROCHLORIDE; H89 DIHYDROCHLORIDE;H 89;(E)-N-(2-(4-bromocinnamylamino)ethyl)isoquinoline-5-sulfonamide dihydrochloride
- CBNumber:
- CB9972711
- Summenformel:
- C20H20BrN3O2S.2ClH.H2O
- Molgewicht:
- 537.304
- MOL-Datei:
- 130964-39-5.mol
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H-89 DIHYDROCHLORIDE HYDRATE Eigenschaften
- Schmelzpunkt:
- 195-200°C
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- H2O: ≥10mg/mL
- Aggregatzustand
- powder
- Farbe
- off-white
H-89 DIHYDROCHLORIDE HYDRATE Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Solid
Verwenden
H-89 dihydrochloride hydrate has been used in the inhibition of protein kinase A in Leydig cells, primary calvarial osteoblasts (pOBs), rat granulosa cell line (LH-15 cells) and human umbilical vein endothelial cells (HUVECs).
Biochem/physiol Actions
H-89 dihydrochloride hydrate is a selective inhibitor of protein kinase A (PKA). It also inhibits potassium (K+) current in rat myocytes. It mediates Na+ transport by interacting with α subunits of epithelial Na+ channel (ENaC).
H-89 DIHYDROCHLORIDE HYDRATE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
H-89 DIHYDROCHLORIDE HYDRATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 119)Lieferanten
130964-39-5()Verwandte Suche:
- H-89 DIHYDROCHLORIDE HYDRATE
- H-89 hydrate dihydrochloride
- H-89 dihydrochloride hydrate,N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride
- 5-IsoquinolinesulfonaMide, N-[2-[[3-(4-broMophenyl)-2-propenyl]aMino]ethyl]-, dihydrochloride
- N-[2-[[3-(4-BroMophenyl)-2-propen-1-yl]aMino]ethyl]-5-isoquinolinesulfonaMide Hydrochloride
- H 89 2HCl
- Protein kinase inhibitor H-89 dihydrochloride
- (E)-N-(2-(4-bromocinnamylamino)ethyl)isoquinoline-5-sulfonamide dihydrochloride
- (E)-N-(2-((3-(4-bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide dihydrochloride
- H-89 Dihydrochloride Hydrate,N-[2-(P-Bromocinnamylamino)Et
- N-[2-[[3-(4-Bromophenyl)-2-Propen-1-Yl]Amino]Ethyl]-5-Isoquinolinesulfonamide Hydrochloride (1:2)
- PROTEIN KINASE INHIBITOR H-89 DIHYDROCHLORIDE; H89 DIHYDROCHLORIDE;H 89
- H-89 dihydrochloride(Protein kinase inhibitor H-89 dihydrochloride)
- PROTEIN KINASE INHIBITOR H-89 DIHYDROCHLORIDE;H89 DIHYDROCHLORIDE;H 89 DIHYDROCHLORIDE;H 89;H89
- 5-Isoquinolinesulfonamide
- H-89 DIHYDROCHLORIDE HYDRATE USP/EP/BP
- Protein kinase inhibitor H-89 dihydrochloride|||H 89 2HCl|||5-Isoquinolinesulfonamide
- 130964-39-5
- Inhibitors
- Akt
- mTOR
- PI3K
- PI3K/Akt/mTOR
- Protein Kinase Inhibitors and Activators
