Ethylene Glycol Methacrylate
- CAS No.
- 868-77-9
- Chemical Name:
- Ethylene Glycol Methacrylate
- Synonyms
- HEMA;GMA;HYDROXYETHYL METHACRYLATE;GLYCOL METHACRYLATE;ETHYLENE GLYCOL METHACRYLATE;BisoMer HEMA;N5-Methyl-L-glutamine;Hydroxyethyl Methacrylat;2-(Methacryloyloxy)ethanol;Hydroxyethyl methacrylate (HEMA)
- CBNumber:
- CB00124245
- Molecular Formula:
- C6H10O3
- Molecular Weight:
- 130.14
- MDL Number:
- MFCD00002863
- MOL File:
- 868-77-9.mol
- MSDS File:
- SDS
| Melting point | -12 °C |
|---|---|
| Boiling point | 67 °C3.5 mm Hg(lit.) |
| Density | 1.073 g/mL at 25 °C(lit.) |
| vapor density | 5 (vs air) |
| vapor pressure | 0.01 mm Hg ( 25 °C) |
| refractive index |
n |
| Flash point | 207 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Methanol (Slightly) |
| pka | 13.83±0.10(Predicted) |
| form | Liquid |
| color | Clear |
| Odor | Ester like |
| Viscosity | 6.36mm2/s |
| Water Solubility | soluble |
| FreezingPoint | -20 |
| FreezingPoint | -96 |
| Sensitive | Air Sensitive |
| BRN | 1071583 |
| Stability | Unstable - may polymerize in the absence of stabilizer. May be stabilized with, or contain small amounts of, diethylene glycol monomethacrylate, di(ethylene glycol)dimethacrylate, methacrylic acid. Incompatible with strong oxidizing agents, free radical initiators, peroxides, steel. Closed containers may explode if heated due to runaway polymer |
| InChIKey | WOBHKFSMXKNTIM-UHFFFAOYSA-N |
| LogP | 0.42 at 25℃ |
| Indirect Additives used in Food Contact Substances | 2-HYDROXYETHYL METHACRYLATE |
| FDA 21 CFR | 175.105; 177.1010 |
| CAS DataBase Reference | 868-77-9(CAS DataBase Reference) |
| EWG's Food Scores | 3-6 |
| FDA UNII | 6E1I4IV47V |
| NIST Chemistry Reference | 2-Hydroxyethyl methacrylate(868-77-9) |
| EPA Substance Registry System | 2-Hydroxyethyl methacrylate (868-77-9) |
| Cosmetics Info | HEMA |
| UNSPSC Code | 12352108 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H317-H319 | |||||||||
| Precautionary statements | P261-P264-P272-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/38-43-36/37/38 | |||||||||
| Safety Statements | 26-36/37-28A-28 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | OZ4725000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29161490 | |||||||||
| Hazardous Substances Data | 868-77-9(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: 5050 mg/kg LD50 dermal Rabbit > 3000 mg/kg | |||||||||
| NFPA 704 |
|
Ethylene Glycol Methacrylate price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.00588 | 2-Hydroxyethyl methacrylate (stabilised with hydroquinone monomethyl ether) for synthesis | 868-77-9 | 250ML | $60.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.00588 | 2-Hydroxyethyl methacrylate (stabilised with hydroquinone monomethyl ether) for synthesis | 868-77-9 | 2.5L | $132 | 2024-03-01 | Buy |
| Sigma-Aldrich | 17348 | 2-Hydroxyethyl methacrylate embedding medium (for microscopy) | 868-77-9 | 250ML | $115 | 2024-03-01 | Buy |
| Sigma-Aldrich | 128635 | 2-Hydroxyethyl methacrylate contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97% | 868-77-9 | 1kg | $52 | 2024-03-01 | Buy |
| Sigma-Aldrich | 128635 | 2-Hydroxyethyl methacrylate contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97% | 868-77-9 | 18kg | $547 | 2024-03-01 | Buy |
Ethylene Glycol Methacrylate Chemical Properties,Uses,Production
Chemical Properties
colourless liquid
Uses
2-Hydroxyethyl methacrylate is used in UV-curable inks and coatings. It is also used in adhesives, artificial nails, dental materials and lacquers. In dentistry, it is one of the main volatile acrylates along with methyl methacrylate. Further, it is used as a monomer in the synthesis of polymers for dental prosthetics and for geotechnical grouting in construction work.
Uses
2-Hydroxyethyl methacrylate is the methacrylic monomer for use in UV inks, adhesives, lacquers, dental materials, artificial nails, etc.
Uses
2-Hydroxyethyl methacrylate is used for preparation of hydrophilic polymers for biomedical devices.
Definition
2-Hydroxyethyl methacrylate is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
General Description
2-Hydroxyethyl methacrylate (HEMA) is biocompatible in nature. Polymeric hydrogel scaffold can be produced by polymerizing HEMA in water.
Hazard
30% grade (with xylene): Flammable, moderate fire risk.
Environmental Fate
2-Hydroxyethyl methacrylate's production and use in acrylic resins, enamels, and as a binder for non-woven fabrics may result in its release to the environment through various waste streams. If released into the air, a vapor pressure of 0.126 mm Hg at 25 °C indicates that 2-hydroxyethyl methacrylate will exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-hydroxyethyl methacrylate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 16 hours. If released to soil, 2-hydroxyethyl methacrylate is expected to have very high mobility based upon an estimated Koc of 43. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 4.6X10-9 atm-cu m/mole. 2-Hydroxyethyl methacrylate is not expected to volatilize from dry soil surfaces based on its vapor pressure. If released into water, 2-hydroxyethyl methacrylate is not expected to adsorb to suspended solids and sediment in the water column based on the estimated Koc. 2-Hydroxyethyl methacrylate reached 92-100% of its theoretical BOD in 2 weeks using an activated sludge inoculum. Volatilization from water surfaces is not expected to be a necessary fate process based on this compound's estimated Henry's Law constant. An estimated BCF of 1.3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis of 2-hydroxyethyl methacrylate may be a significant process under basic conditions based upon a hydrolytic half-life of 4 hours at pH 11 for the structurally similar butyl acrylate; half-lives for butyl acrylate at pH 7, 8, and 9 were 4 years, 150 days, and 15 days, respectively. Occupational exposure to 2-hydroxyethyl methacrylate may occur through inhalation and dermal contact with this compound at workplaces where 2-hydroxyethyl methacrylate is produced or used. The general population may be exposed to 2-hydroxyethyl methacrylate via inhalation or dermal contact with acrylic resins or enamels containing this compound.
Metabolism
2-hydroxyethyl methacrylate (HEMA) is a monomer based on methacrylic acid (MAA) used to produce biomaterials such as dental adhesive and composite resins. The process of polymerization, which is run in situ, is always incomplete, resulting in the presence of free monomers in the oral cavity. Moreover, monomers can be released from polymer-based tooth restorations through mechanical shearing and enzymatic degradation of polymers. They may penetrate the pulp through microchannels in the dentin structure. HEMA, like many of MAA-based monomers, is an ester, so it can be targeted by esterases when in organism and can undergo degradation. The main product of HEMA hydrolysis is MAA, which may undergo further degradation producing several intermediates of potential biological activity[1].
Purification Methods
Dissolve the ester in water and extract with n-heptane to remove ethylene glycol dimethacrylate (checked by gas-liquid chromatography and by NMR) and distil it twice under reduced pressure [Strop et al. J Phys Chem 80 694 1976]. [Beilstein 2 IV 1530.]
Toxics Screening Level
The ITSL can be determined from the mouse LD50 from Tanii and Hashimoto using the
equation from R232(1)(h) as follows.
ITSL = (5887 mg/kg)/( 500x 40 x 100 x 0.167) x 1kg/1.7m3 = 10 μg/m3 annual average.
The default mouse inhalation rate of 1.7 m3/kg was used in the above calculation.
Ethylene Glycol Methacrylate Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 | sales@qinmuchem.com | China | 1009 | 58 |
| Yancheng Green Chemicals Co.,Ltd | +undefined-86-25-86655873 | info@royal-chem.com | China | 114 | 58 |
| Shijiazhuang Tongyang Import and Export Co., LTD | 18031361688; | admin@sjztongyang.com | China | 977 | 58 |
| Qingdao RENAS Polymer Material Co., Ltd. | +86-0532-86867058 +86-18562606086 | sales@qdrenas.com | China | 476 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615350571055 | Sibel@weibangbio.com | China | 6087 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3007 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20267 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
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View Lastest Price from Ethylene Glycol Methacrylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-11 | Ethylene glycol methacrylate phosphate
24599-21-1
|
US $9.00-70.00 / g | 10g | 99% | 10 tons | Hebei Kangcang new material Technology Co., LTD | |
 |
2023-12-23 | ETHYLENE GLYCOL METHACRYLATE PHOSPHATE
24599-21-1
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2021-03-17 | ETHYLENE GLYCOL METHACRYLATE PHOSPHATE
24599-21-1
|
US $60.00 / KG | 1g | 99.8% | 10tons | Hebei shuoxi biotechnology co. LTD |
-
- Ethylene glycol methacrylate phosphate
24599-21-1
- US $9.00-70.00 / g
- 99%
- Hebei Kangcang new material Technology Co., LTD
-
- ETHYLENE GLYCOL METHACRYLATE PHOSPHATE
24599-21-1
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- ETHYLENE GLYCOL METHACRYLATE PHOSPHATE
24599-21-1
- US $60.00 / KG
- 99.8%
- Hebei shuoxi biotechnology co. LTD