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Amantadine Hcl

Amantadine Hcl structure

CAS No.: 665-66-7

Chemical Name:: Amantadine Hcl

Synonyms: AMANTADINE HCL;AMANTADINE HYDROCHLORIDE;1-AMINOADAMANTANE HYDROCHLORIDE;symmetrel;1-ADAMANTANAMINE HCL;Mantadan;ADAMANTANAMINE HYDROCHLORIDE;Amantadine hydrochloride,1-Adamantanamine hydrochloride, 1-Adamantylamine hydrochloride, 1-Aminoadamantane hydrochloride;Adekin;virasol

CBNumber:: CB00128587

Molecular Formula:: C10H18ClN

Molecular Weight:: 187.71

MDL Number:: MFCD00074723

MOL File:: 665-66-7.mol

MSDS File:: SDS

Last updated:2024-08-24 19:19:26

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Amantadine Hcl Properties

Melting point	>300 °C(lit.)
Boiling point	308.63°C (rough estimate)
Density	1.0276 (rough estimate)
refractive index	1.6100 (estimate)
storage temp.	Store below +30°C.
solubility	H₂O: 50 mg/mL
form	Fine Crystalline Powder
color	White
Water Solubility	soluble
Sensitive	Hygroscopic
Merck	14,374
BRN	4198854
InChIKey	WOLHOYHSEKDWQH-UHFFFAOYSA-N
LogP	-1.64 at 23℃ and pH6.3
CAS DataBase Reference	665-66-7(CAS DataBase Reference)
FDA UNII	M6Q1EO9TD0
NCI Dictionary of Cancer Terms	amantadine hydrochloride
NCI Drug Dictionary	amantadine hydrochloride
Proposition 65 List	Amantadine Hydrochloride
EPA Substance Registry System	Amantadine hydrochloride (665-66-7)

Pharmacokinetic data

Protein binding	67%
Excreted unchanged in urine	90%
Volume of distribution	5-10(L/kg)
Biological half-life	15 / 500

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312+P330

Hazard Codes

Risk Statements

22-40-20/21/22

Safety Statements

22-36/37-36-35-20/21

RIDADR

UN 1759 8 / PGII

WGK Germany

RTECS

AU4375000

TSCA

Yes

HazardClass

IRRITANT

HS Code

29213000

Toxicity

LD50 orally in mice, rats: 700, 1275 mg/kg (Vernier)

NFPA 704

	1
3		0

Amantadine Hcl price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A1260	Amantadine hydrochloride	665-66-7	5g	$65.9	2024-03-01	Buy
Sigma-Aldrich	BP530	Amantadine hydrochloride British Pharmacopoeia (BP) Reference Standard	665-66-7	200MG	$257	2024-03-01	Buy
Sigma-Aldrich	8.20015	1-Adamantaneammonium chloride for synthesis	665-66-7	10g	$66.1	2024-03-01	Buy
Sigma-Aldrich	8.20015	1-Adamantaneammonium chloride for synthesis	665-66-7	50g	$241	2024-03-01	Buy
Sigma-Aldrich	1018505	Amantadine hydrochloride United States Pharmacopeia (USP) Reference Standard	665-66-7	200mg	$436	2024-03-01	Buy

Product number	Packaging	Price	Buy
A1260	5g	$65.9	Buy
BP530	200MG	$257	Buy
8.20015	10g	$66.1	Buy
8.20015	50g	$241	Buy
1018505	200mg	$436	Buy

Amantadine Hcl Chemical Properties,Uses,Production

Description

Amantadine Hcl is in a class of medications called adamantanes. It is thought to work to control movement problems by increasing the amount of dopamine in certain parts of the body. It works against influenza A virus by stopping the spread of the virus in the body. Amantadine is used to treat the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) and other similar conditions.

Uses

Amantadine Hcl is an antidyskinetic medicine. It is used to treat Parkinson's disease (sometimes called "paralysis agitans" or "shaking palsy") and its symptoms, including dyskinesia (sudden uncontrolled movements). It may be given alone or in combination with other medicines (eg, levodopa) for Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced. Amantadine is also used to treat stiffness and shakiness caused by certain medicines that are used to treat nervous, mental, and emotional conditions.

Side effects

Blurred vision, nausea, stomach upset, drowsiness, dizziness, headache, dry mouth, constipation, nervousness, or trouble sleeping may occur.

Amantadine Hcl synthesis

Synthesis of Amantadine Hcl from Amantadine

Amantadine Hcl Preparation Products And Raw materials

Raw materials

Aluminium-nickel Amantadine Dicyclopentadiene Sodium sulfite Chlorine

Urea Aluminum chloride Hydrochloric acid Hydrogen Government regulation

Sodium hydroxide HYDROGEN CYANIDE Adamantane 2-Adamantanamine hydrochloride

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Preparation Products

Amantadine Hcl Suppliers

Global( 630)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Qiwei Pharmatech Co.,Ltd	13282840061	mw@qwpharmatech.com	China	109	58
Huzhou Chenxi Environmental Protection Technology Co. , Ltd.	+8616762203950	1034385273@qq.com	China	55	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177; +8617531190177	peter@yan-xi.com	China	5872	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5870	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	1143	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	+8615383190639	admin@86-ss.com	China	1000	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29798	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Shanghai Bojing Chemical Co.,Ltd.	+86-86-02137122233 +8613795318958	bj1@bj-chem.com	China	299	55

Supplier	Advantage
Hangzhou Qiwei Pharmatech Co.,Ltd	58
Huzhou Chenxi Environmental Protection Technology Co. , Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Nantong Guangyuan Chemicl Co,Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Shanghai Bojing Chemical Co.,Ltd.	55

1-Adamantanamine hydrochloride:an antiviral substance
1-Adamantanamine hydrochloride is a synthetic organic compound with highly soluble, relatively non-toxic, and biologically sta....
Nov 16，2023

View Lastest Price from Amantadine Hcl manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-11	Amantadine HCl 665-66-7	US $0.00 / kg	1kg	99%	1000kg	Shaanxi TNJONE Pharmaceutical Co., Ltd
2021-11-18	Amantadine 768-94-5	US $10.00 / Kg/Bag	1Kg/Bag	99%	20 Tons	Hebei Zhanyao Biotechnology Co. Ltd
2021-07-22	Amantadine 768-94-5	US $10.00 / KG	100KG	99%	100 mt	Hebei Guanlang Biotechnology Co., Ltd.

Amantadine HCl
665-66-7
US $0.00 / kg
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Amantadine
768-94-5
US $10.00 / Kg/Bag
99%
Hebei Zhanyao Biotechnology Co. Ltd

Amantadine
768-94-5
US $10.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

1-Adamantanamine hydrochloride Spectrum

1-Adamantanamine hydrochloride(665-66-7)MS 1-Adamantanamine hydrochloride(665-66-7)¹HNMR 1-Adamantanamine hydrochloride(665-66-7)¹³CNMR 1-Adamantanamine hydrochloride(665-66-7)IR1 1-Adamantanamine hydrochloride(665-66-7)IR2 1-Adamantanamine hydrochloride(665-66-7)Raman

665-66-7(Amantadine Hcl)Related Search:

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Amantadine Hydrochloride (200 mg) 1-AdaMantanaMine hydrochloride, 99+% 100GR 1-AdaMantanaMine hydrochloride, 99+% 25GR 1-AdaMantanaMine hydrochloride, 99+% 5GR 1-adamantane amine hydrochloride 1-Adamantanamine Hydrochleride 1-Aminoadamantane Hydrochloride Amantadine Hydrochloride Adamantan-1-amine hydrochloride, Tricyclo[3.3.1.1~3,7~]decan-1-amine hydrochloride, Amantadine hydrochloride AMantadine HCl USP 1-adamantylammonium chloride 1-adamantylazanium chloride 1-Aminoadamantene hydrochlorid adamantan-1-aminium chloride tricyclo[3.3.1.1(3,7)]decan-1-aminium chloride Tricyclo[3.3.1.13,7]decan-1-amine, hydrochloride (1:1) aminoadamantanehydrochloride exp105-1 midantane mydantane nsc83653 tricyclo(3.3.1.1(sup3,7))decan-1-amine,hydrochloride 1-Adamantanamine hydrochloride, 1-Adamantylamine hydrochloride, Amantadine hydrochloride 1-Adamantanamine hydrochloride, 1-Adamantylamine hydrochloride, 1-Aminoadamantane hydrochloride TIMTEC-BB SBB003680 TRICYCLODECANE HYDROCHLORIDE ADAMANTAN-1-AMINE HYDROCHLORIDE 1-aminoadamantenehydrochloride 1-ADAMANTYLAMINE HYDROCHLORIDE 1-ADAMANTANAMINE HYDROCHLORIDE 1-ADAMANTANEAMMONIUM CHLORIDE adamantinehydrochloride adamantylaminehydrochloride tricyclo[3.3.1.13,7]decan-1-amine,hydrochloride virasol AMANTADINE HYDROCHLORIDE, PHARMA Adekin Lysovir Mantadix Virofral AMANTADINEHYDROCHLORIDE,USP 1-Adamantamine hydrochloride 1-Adamantanamine, hydrochloride (8CI) Adamantanamine hydrochloride (6CI) Amazolon Midantan 1-ADAMANTANAMINE HYDROCHLORIDE, 99+% 1-Adamantaneammonium chloride for synthesis 1-Adamantanamin Hydrochlorid 1-Adamantanamine HydrochL 1-adamantylammonium Adamantane Hydrocloride 1-Adamantanamine hydrochloride intermediate 1-Adamantanamine Hydrochloride [Amantadine Hydrochloride] Amintadine Hcl 1-Amantadine hydrochloride (3s,5s,7s)-adamantan-1-amine hydrochloride 1-Adamantanamine hydrochloride, 99%, antiviral and antiparkinsonian compound Memantine Impurity 13