ChemicalBook >> CAS DataBase List >>4-Amidinophenylmethanesulfonyl fluoride hydrochloride
4-Amidinophenylmethanesulfonyl fluoride hydrochloride
- CAS No.
- 74938-88-8
- Chemical Name:
- 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
- Synonyms
- 4-APMSF;P-APMSF;APMSF HCL;Nsc727369;uoride hydrochL;4-AmidinophenyL;APMSF HYDROCHLORIDE;4-Amidinophenylmetha;P-APMSF, HYDROCHLORIDE;p-APMSF, Hydrochloride
- CBNumber:
- CB0113452
- Molecular Formula:
- C8H10ClFN2O2S
- Molecular Weight:
- 252.69
- MDL Number:
- MFCD00036898
- MOL File:
- 74938-88-8.mol
- MSDS File:
- SDS
Last updated:2025-04-18 09:51:26
| Melting point | ~205 °C (dec.) |
|---|---|
| storage temp. | -20°C |
| solubility | H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems. |
| form | White solid |
| color | white |
| Water Solubility | water: 25mg/mL |
| BRN | 9083148 |
| InChIKey | KHLLRHIUKOJXLL-UHFFFAOYSA-N |
| CAS DataBase Reference | 74938-88-8(CAS DataBase Reference) |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P280-P303+P361+P353-P301+P330+P331-P304+P340+P310-P305+P351+P338+P310 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 29252900 |
4-Amidinophenylmethanesulfonyl fluoride hydrochloride price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 178281 | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride Alternative to DFP and PMSF. | 74938-88-8 | 5mg | $172 | 2024-03-01 | Buy |
| Sigma-Aldrich | A6664 | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride serine protease inhibitor | 74938-88-8 | 10mg | $175 | 2023-01-07 | Buy |
| Cayman Chemical | 14971 | p-APMSF (hydrochloride) | 74938-88-8 | 5mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 14971 | p-APMSF (hydrochloride) | 74938-88-8 | 25mg | $356 | 2024-03-01 | Buy |
| Sigma-Aldrich | A6664 | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride serine protease inhibitor | 74938-88-8 | 50mg | $600 | 2023-01-07 | Buy |
4-Amidinophenylmethanesulfonyl fluoride hydrochloride Chemical Properties,Uses,Production
Description
p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.
Uses
p-APMSF is an irreversible inhibitor of serinase. p-APMSF has substrate specificity for positively charged side chains of amino acids, lysine, or arginine. p-APMSF can be used to study the irreversible inhibition of trypsin and thrombin [1].
Biochem/physiol Actions
Irreversible inhibitor of serine proteases with lysine or arginine substrate specificities. Effective concentration 10-100 μM. Frequently used to characterize newly discovered proteases.
References
[1] Laura R, et al. (p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitor of serine proteases. Biochemistry. 1980 Oct 14;19(21):4859-64. DOI:10.1021/bi00562a024
4-Amidinophenylmethanesulfonyl fluoride hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 84)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22858 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
View Lastest Price from 4-Amidinophenylmethanesulfonyl fluoride hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-11 | 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
74938-88-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
74938-88-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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