4-Methylvaleric acid
- CAS No.
- 646-07-1
- Chemical Name:
- 4-Methylvaleric acid
- Synonyms
- 4-METHYLPENTANOIC ACID;PENTANOIC ACID, 4-METHYL-;ISOCAPROIC ACID;ISOHEXANOIC ACID;FEMA 3463;isohexoicacid;isocaproicaci;Isohexoic acid;Isocapronsαure;4-Methylvaleri
- CBNumber:
- CB1483316
- Molecular Formula:
- C6H12O2
- Molecular Weight:
- 116.16
- MDL Number:
- MFCD00002803
- MOL File:
- 646-07-1.mol
- MSDS File:
- SDS
| Melting point | -35 °C |
|---|---|
| Boiling point | 199-201 °C (lit.) |
| Density | 0.923 g/mL at 25 °C (lit.) |
| FEMA | 3463 | 4-METHYLPENTANOIC ACID |
| refractive index |
n |
| Flash point | 207 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| pka | 4.84(at 18℃) |
| form | Liquid |
| Specific Gravity | 0.923 |
| color | Clear colorless to slightly yellow |
| Odor | at 1.00 % in propylene glycol. pungent cheese |
| Odor Type | cheesy |
| Odor Threshold | 0.0004ppm |
| Water Solubility | INSOLUBLE |
| JECFA Number | 264 |
| BRN | 1741912 |
| Stability | Stable. Incompatible with strong bases, strong oxidizing agents. |
| InChIKey | FGKJLKRYENPLQH-UHFFFAOYSA-N |
| LogP | 1.66 |
| Substances Added to Food (formerly EAFUS) | 4-METHYLPENTANOIC ACID |
| CAS DataBase Reference | 646-07-1(CAS DataBase Reference) |
| FDA UNII | 4G4U8JA28T |
| NIST Chemistry Reference | Pentanoic acid, 4-methyl-(646-07-1) |
| EPA Substance Registry System | Pentanoic acid, 4-methyl- (646-07-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H311-H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P361+P364-P405 | |||||||||
| Hazard Codes | Xn,C | |||||||||
| Risk Statements | 21-38-34 | |||||||||
| Safety Statements | 36/37-45-36/37/39-25 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NR2975000 | |||||||||
| F | 13 | |||||||||
| TSCA | T | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159080 | |||||||||
| NFPA 704 |
|
4-Methylvaleric acid price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W346306 | 4-Methylpentanoic acid ≥98%, FCC, FG | 646-07-1 | 250g | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | W346306 | 4-Methylpentanoic acid ≥98%, FCC, FG | 646-07-1 | 1kg | $458 | 2024-03-01 | Buy |
| Sigma-Aldrich | W346306 | 4-Methylpentanoic acid ≥98%, FCC, FG | 646-07-1 | 10Kg | $3170 | 2024-03-01 | Buy |
| Sigma-Aldrich | 277827 | 4-Methylvaleric acid 99% | 646-07-1 | 5g | $30.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 277827 | 4-Methylvaleric acid 99% | 646-07-1 | 25g | $103 | 2024-03-01 | Buy |
4-Methylvaleric acid Chemical Properties,Uses,Production
Description
4-Methylpentanoic acid has an unpleasant sour and penetrating odor.
Chemical Properties
slightly brown liquid
Chemical Properties
4-Methylpentanoic acid has an unpleasant, sour, penetrating odor.
Occurrence
Reported found in apple, roasted barley, beef, prefermented bread, Camembert cheese, Emmenthal cheese, roasted cocoa beans, dry cured ham, hops, roasted pecans, rum, soybeans, black tea, wine, guava, papaya, strawberry fruit and jam, baked potato, bell pepper, tomato, many cheeses, fish, beef, mutton, hop oil, mushrooms, mango, rice, sake, malt, wort, dried bonito and mussels
Uses
Intermediate for plasticizers, pharmaceuticalsand perfumes.
Uses
4-Methylvaleric acid has been used in asymmetric synthesis of (4S)-4-isopropyl-3-[(2?S)-2?,4?-dimethyl-valeryl)]-2-oxazolidinone. It is a versatile building block used in the synthesis of various pharmaceutical and biologically active compounds, including inhibitors and antagonists. It is involved in the synthesis of novel series of high affinity, functionally potent antagonists of the CCR1 receptor.
Uses
4-Methylvaleric acid has been used in asymmetric synthesis of (4S)-4-isopropyl-3-[(2′S)-2′,4′-dimethyl-valeryl)]-2-oxazolidinone.
Definition
ChEBI: A methyl-branched fatty acid that is pentanoic acid with a methyl group substituent at position 4. It is a metabolite of 20 alpha-hydroxycholesterol
Application
4-Methylvaleric acid, although identified in Nature, has found very little, if any, use in perfumes or flavors. It is mentioned mainly for the sake of completing the monographs on Methylpentanoic acids.
Aroma threshold values
Detection: 810 ppb.
Synthesis Reference(s)
The Journal of Organic Chemistry, 40, p. 1844, 1975 DOI: 10.1021/jo00900a040
General Description
Conductimetric detection of 4-methylvaleric acid on unfunctionized polymethacrylate resin (TSKgel G3000PWXL) columns has been reported.
4-Methylvaleric acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Xiangduo Industry Co., Ltd. | +86-15981848961 +86-15981848961 | sales@xiangduochem.com | China | 497 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8817 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12837 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20288 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 660 | 58 |
| JINING XINHE CHEMICAL CO., LTD | +8615318402391 | sales@xinhepharma.com | China | 808 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21638 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32820 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29885 | 58 |
View Lastest Price from 4-Methylvaleric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-04 | 4-Methylpentanoic acid
646-07-1
|
US $29.00 / mL | 99.26% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-10-24 | 4-Methylvaleric acid
646-07-1
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-10-23 | 4-Methylvaleric acid
646-07-1
|
US $6.90-4.20 / kg | 1kg | 99% | 10 tons | Shandong Deshang Chemical Co., Ltd. |
-
- 4-Methylpentanoic acid
646-07-1
- US $29.00 / mL
- 99.26%
- TargetMol Chemicals Inc.
-
- 4-Methylvaleric acid
646-07-1
- US $1.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- 4-Methylvaleric acid
646-07-1
- US $6.90-4.20 / kg
- 99%
- Shandong Deshang Chemical Co., Ltd.