Fmoc-Trp(Boc)-OH
- CAS No.
- 143824-78-6
- Chemical Name:
- Fmoc-Trp(Boc)-OH
- Synonyms
- FMOC-L-TRP(BOC)-OH;FMOC-TRP(BOC);FMOC-L-TRP(BOC);N1-Boc-NaL;pha-Fmoc-L;FMOC-TRP(BOC)-OH;Fomc-Trp(Boc)-OH;Fmoc-Trp(Boc)-0H;FMOC-L-TRYPTOPHANE;FMOC-L-TRP(TBOC)-OH
- CBNumber:
- CB3360314
- Molecular Formula:
- C31H30N2O6
- Molecular Weight:
- 526.58
- MDL Number:
- MFCD00153366
- MOL File:
- 143824-78-6.mol
- MSDS File:
- SDS
Melting point | ca 97℃ |
---|---|
alpha | -21 º (c=1%, DMF) |
Density | 1.28±0.1 g/cm3(Predicted) |
refractive index | -20 ° (C=1, DMF) |
storage temp. | 2-8°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | Solid |
pka | 3.71±0.10(Predicted) |
color | White to Orange to Green |
optical activity | [α]20/D 21±2°, c = 1% in DMF |
Sensitive | Moisture Sensitive |
BRN | 7698009 |
InChIKey | ADOHASQZJSJZBT-SANMLTNESA-N |
CAS DataBase Reference | 143824-78-6(CAS DataBase Reference) |
FDA UNII | X3V4CFM5R8 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H317-H401-H411 | |||||||||
Precautionary statements | P261-P280g-P302+P352a-P321-P333+P313-P501a | |||||||||
Hazard Codes | Xi,N | |||||||||
Risk Statements | 36/37/38-51/53-43 | |||||||||
Safety Statements | 22-24/25-36/37/39-27-26-61-37-24 | |||||||||
RIDADR | 3077 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-21 | |||||||||
HazardClass | 9 | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
Fmoc-Trp(Boc)-OH price More Price(51)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.52050 | Fmoc-Trp(Boc)-OH Novabiochem? | 143824-78-6 | 25g | $196 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52050 | Fmoc-Trp(Boc)-OH Novabiochem? | 143824-78-6 | 100g | $511 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52050 | Fmoc-Trp(Boc)-OH Novabiochem? | 143824-78-6 | 250g | $1090 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.52050 | Fmoc-Trp(Boc)-OH Novabiochem? | 143824-78-6 | 1kg | $4080 | 2024-03-01 | Buy |
Sigma-Aldrich | 47561 | Fmoc-Trp(Boc)-OH ≥97.0% (HPLC) | 143824-78-6 | 5G | $71.2 | 2024-03-01 | Buy |
Fmoc-Trp(Boc)-OH Chemical Properties,Uses,Production
Chemical Properties
White solid
Uses
Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of glucagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes and various peptides by Fmoc solid phase peptide synthesis (SPPS).
Uses
Fmoc-Trp(Boc)-OH is a very useful synthetic intermediate. It is used to prepare Trp containing-peptides.
General Description
The use of this N-in-Boc protected derivative overcomes most of the problems associated with the preparation of Trp containing-peptides by Fmoc SPPS [1]. Cleavage with TFA generates an N-in-carboxy indole which protects the Trp from alkylation [1, 2, 3] and sulfonation [1, 4, 5, 6, 7]. The N-in-carboxy group is removed under aqueous conditions during normal work-up of the peptide.
The product number for this product was previously 04-12-1103.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
![405555-31-9](/CAS/20210305/GIF/405555-31-9.gif)
![4425-82-5](/CAS/GIF/4425-82-5.gif)
![143824-78-6](/CAS/GIF/143824-78-6.gif)
Fmoc-Trp(Boc)-OH Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chemtour Biotech Co., Ltd | +8617327281506 | market@chemtour.com | China | 1460 | 58 |
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 894 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9332 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
View Lastest Price from Fmoc-Trp(Boc)-OH manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-23 | Fmoc-Trp(Boc)-OH
143824-78-6
|
US $5.00 / kg | 1kg | ≥99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
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2024-08-22 | Fmoc-Trp(Boc)-OH
143824-78-6
|
US $0.00 / Kg/Drum | 1KG | 98%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
![]() |
2024-08-20 | Fmoc-Trp(Boc)-OH
143824-78-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd |
-
- Fmoc-Trp(Boc)-OH
143824-78-6
- US $5.00 / kg
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- Fmoc-Trp(Boc)-OH
143824-78-6
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Fmoc-Trp(Boc)-OH
143824-78-6
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd