ChemicalBook >> CAS DataBase List >>POMALIDOMIDE-PEG2-CO2H
POMALIDOMIDE-PEG2-CO2H
- CAS No.
- 2140807-17-4
- Chemical Name:
- POMALIDOMIDE-PEG2-CO2H
- Synonyms
- NUN 07174;Poma-PEG2-COOH;Pomalidomide-PEG2-COOH;POMALIDOMIDE-PEG2-CO2H;Pomalidomide-PEG2-Acid;Thalidomide-4-NH-PEG2-COOH;Thalidomide-NH-PEG2-C2-COOH;Pomalidomide-PEG2-CO2H >=98%;Thalidomide-4-NH-PEG2-C2-COOH;3-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]propanoic Acid
- CBNumber:
- CB44744117
- Molecular Formula:
- C20H23N3O8
- Molecular Weight:
- 433.41
- MDL Number:
- MFCD32173785
- MOL File:
- 2140807-17-4.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:09
POMALIDOMIDE-PEG2-CO2H Chemical Properties,Uses,Production
Uses
Protein degrader builiding block Pomalidomide-PEG2-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
storage
Store at -20°C
POMALIDOMIDE-PEG2-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
POMALIDOMIDE-PEG2-CO2H Suppliers
Global( 34)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12945 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3152 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 6000 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Xi‘an Deeptech Biotechnology Co.,LTD | 15114901355 | 15114901355@163.com | China | 183 | 58 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6943 | 65 |
| ChemShuttle, Inc. | 0510-83588313-802 18800520310; | sales@chemshuttle.com | China | 2993 | 62 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25014 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
View Lastest Price from POMALIDOMIDE-PEG2-CO2H manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | Pomalidomide-PEG2-COOH
2140807-17-4
|
US $0.00 / mg | 100mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
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- Pomalidomide-PEG2-COOH
2140807-17-4
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
2140807-17-4(POMALIDOMIDE-PEG2-CO2H)Related Search:
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG2-N3
Pomalidomide-PEG4-azide
Pomalidomide-PEG2-butyl iodide
E3 Ligase Ligand-Linker Conjugates 22
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pomalidomide-PEG4-CO2H
E3 Ligase Ligand-Linker Conjugates 1
Pomalidomide-PEG1-azide
Pomalidomide-PEG5-CO2H
1of4
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG2-COOH
Pomalidomide-PEG2-CO2H >=98%
NUN 07174
Thalidomide-4-NH-PEG2-COOH
Thalidomide-NH-PEG2-C2-COOH
Propanoic acid, 3-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]-
3-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]propanoic Acid
Thalidomide-4-NH-PEG2-C2-COOH
3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic Acid
Poma-PEG2-COOH
Pomalidomide-PEG2-Acid
2140807-17-4
APIs
peg