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AC-LEHD-AFC

CAS No.
210345-03-2
Chemical Name:
AC-LEHD-AFC
Synonyms
AC-LEHD-AFC;Ac-LEHD-AFC TFA salt;AC-LEU-GLU-HIS-ASP-AFC;CASPASE-9 SUBSTRATE I, FLUOROGENIC;CASPASE 9 SUBSTRATE 1F, FLUOROGENIC;AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)
CBNumber:
CB6377625
Molecular Formula:
C33H38F3N7O11
Molecular Weight:
765.69
MDL Number:
MFCD01862610
MOL File:
210345-03-2.mol
Last updated:2023-05-18 11:31:05

AC-LEHD-AFC Properties

Boiling point 1211.9±65.0 °C(Predicted)
Density 1.457±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO/DMF: 20 mM
form powder
pka 4.07±0.10(Predicted)
color white
Water Solubility Soluble to 1 mg/ml in water

SAFETY

Risk and Safety Statements

WGK Germany  3

AC-LEHD-AFC price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 218765 Caspase-9 Substrate I, Fluorogenic A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). 1MG $155 2024-03-01 Buy
Sigma-Aldrich 218765 Caspase-9 Substrate I, Fluorogenic A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). 5MG $425 2024-03-01 Buy
Cayman Chemical 17051 Ac-LEHD-AFC ≥95% 210345-03-2 5mg $120 2021-12-16 Buy
Cayman Chemical 17051 Ac-LEHD-AFC ≥95% 210345-03-2 1mg $40 2021-12-16 Buy
Cayman Chemical 17051 Ac-LEHD-AFC ≥95% 210345-03-2 10mg $220 2021-12-16 Buy
Product number Packaging Price Buy
218765 1MG $155 Buy
218765 5MG $425 Buy
17051 5mg $120 Buy
17051 1mg $40 Buy
17051 10mg $220 Buy

AC-LEHD-AFC Chemical Properties,Uses,Production

Uses

Ac-LEHD-AFC Trifluoroacetic Acid Salt is a fluorogenic substrate that is cleaved by caspases (4,5 and 9). This activity is quantified by fluorescent detection of free AFC. Caspase-9 activation is critical for intrinsic cell death.

Biological Activity

Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.

AC-LEHD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

AC-LEHD-AFC Suppliers

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2943 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599 info@molchanges.com China 5225 58
DONBOO AMINO ACID COMPANY
+8613063595538 donboo@donboo.com China 9363 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN) N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN AC-LEU-GLU-HIS-ASP-AFC CASPASE-9 SUBSTRATE I, FLUOROGENIC CASPASE 9 SUBSTRATE 1F, FLUOROGENIC AC-LEHD-AFC L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI) 4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid Ac-LEHD-AFC TFA salt 210345-03-2 C33H38F3N7O11 C33H38O11N7F3 Caspases/Apoptosis peptide