ascochlorin

CAS No.: 26166-39-2

Chemical Name:: ascochlorin

Synonyms: Nsc 287492;ascochlorin;Ilicicolin D;Ll-Z 1272 gamma;Antibiotics LL-Z 1272g;Antibiotic ll-Z1272 gamma;LL-Z 1272 gaMMa, Ilicicolin D;beta-Resorcylaldehyde, 5-chloro-6-methyl-3-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (E,E)-;5-Chloro-2,4-dihydroxy-6-methyl-3-[(2E,4Z)-3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)penta-2,4-dienyl]benzaldehyde;3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1R)-1β,2β,6β-trimethyl-3-oxocyclohexyl]-2,4-pentadienyl]benzaldehyde

CBNumber:: CB01364846

Molecular Formula:: C23H29ClO4

Molecular Weight:: 404.931

MOL File:: 26166-39-2.mol

MSDS File:: SDS

Modify Date:: 2023/5/18 11:31:17

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ascochlorin Properties

Melting point	172-174 °C
Boiling point	556.9±39.0 °C(Predicted)
Density	1.199±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO: soluble
form	A powder
pka	6.26±0.50(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany	3
Toxicity	mouse,LD50,intraperitoneal,20mg/kg (20mg/kg),Journal of Antibiotics. Vol. 21, Pg. 539, 1968.

ascochlorin Chemical Properties,Uses,Production

Uses

Ascochlorin is an antitumor fungal metabolite which specifically inhibits matrix metalloproteinase-9 (MMP-9) activity through suppression of activator protein-1 (AP-1)-dependent induction of MMP-9 gene expression. Via AP-1 suppression, ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses.

ascochlorin Preparation Products And Raw materials

Raw materials

Preparation Products

ascochlorin Suppliers

Global( 28)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
TargetMol Chemicals Inc.	15002134094	China	28118	58	Inquiry
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	China	2992	58	Inquiry
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	China	5014	58	Inquiry
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	China	29778	58	Inquiry
cjbscvictory	13348960310 13348960310	China	10011	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
TargetMol Chemicals Inc.	58
BOC Sciences	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
Suzhou Zhixin Biotechnology Co., Ltd.	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
cjbscvictory	58

26166-39-2(ascochlorin)Related Search:

LF163892 MONOHYDRATE A-1331852 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL 2-ALLYL-6-CHLOROPHENOL ILICICOLIN F

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3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1R)-1β,2β,6β-trimethyl-3-oxocyclohexyl]-2,4-pentadienyl]benzaldehyde Ilicicolin D 3-Chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)benzaldehyde (1R-(1alpha(2E,4E),2beta,6beta))- Antibiotic ll-Z1272 gamma ascochlorin Benzaldehyde, 3-chloro-4,6-dihydroxy-2-methyl-5-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (1R-(1alpha(2E,4E),2beta,6beta))- beta-Resorcylaldehyde, 5-chloro-6-methyl-3-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (E,E)- Ll-Z 1272 gamma Nsc 287492 LL-Z 1272 gaMMa, Ilicicolin D 5-Chloro-2,4-dihydroxy-6-methyl-3-[(2E,4Z)-3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)penta-2,4-dienyl]benzaldehyde Antibiotics LL-Z 1272g Benzaldehyde, 3-chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1R,2R,6R)-1,2,6-trimethyl-3-oxocyclohexyl]-2,4-pentadien-1-yl]- 26166-39-2