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Fluorexon

Fluorexon Structure
CAS No.
1461-15-0
Chemical Name:
Fluorexon
Synonyms
CALCEIN;CALCEINE;FLUOREXON;FLUREXONE;N,N'-[[3';FLUOREXONE;Oftasceine;oftasccine;Nsc 298193;CALCEIN(RG)
CBNumber:
CB0146553
Molecular Formula:
C30H26N2O13
Molecular Weight:
622.53
MOL File:
1461-15-0.mol
MSDS File:
SDS
Modify Date:
2024/8/14 11:12:44
Request For Quotation

Fluorexon Properties

Melting point 200 °C
Boiling point 662.7°C (rough estimate)
Density 1.4388 (rough estimate)
refractive index 1.5800 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility H2O: soluble
form Powder
pka 6.67(at 25℃)
color Yellow-orange to orange-brown
PH Range Weak green ' uorescence (6.0) to strong green ' uorescence (7.2)
Water Solubility insoluble
λmax 494nm
Stability Stable. Incompatible with strong oxidizing agents.
Biological Applications Calcium indicator; fluoride indicator; iron indicator; mercury indicator; detecting nucleic acids,proteins; treating osteoporosis; drug delivery systems
Major Application Chemical-mechanical polishing, stabilizing liposomes, cell motility assay, detecting nucleic acids, virus, screening safety of gastric mucosa, MDR inhibitors, delivery, imaging atherosclerotic plaque
CAS DataBase Reference 1461-15-0(CAS DataBase Reference)
EPA Substance Registry System Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl)bis(methylene)]bis[N-(carboxymethyl)- (1461-15-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H302-H335-H312-H315-H332
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  22-24/25-36/37/39-26
WGK Germany  3
F  10
HS Code  32041900
NFPA 704
0
3 0

Fluorexon price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 1.02315 Calcein indicator for metal determination 1461-15-0 5G ₹16040 2022-06-14 Buy
ottokemi C 1335 Calcein, GR 1461-15-0 1gm ₹216 2022-05-26 Buy
ottokemi C 1335 Calcein, GR 1461-15-0 5gm ₹792 2022-05-26 Buy
ottokemi C 1335 Calcein, GR 1461-15-0 25gm ₹3249 2022-05-26 Buy
SRL 65201 Calcein Reagent extrapure AR (Fluorescein Complexone) 1461-15-0 1Gms ₹260 2022-05-26 Buy
Product number Packaging Price Buy
1.02315 5G ₹16040 Buy
C 1335 1gm ₹216 Buy
C 1335 5gm ₹792 Buy
C 1335 25gm ₹3249 Buy
65201 1Gms ₹260 Buy

Fluorexon Chemical Properties,Uses,Production

Chemical Properties

orange crystals

Uses

Calcein is used for determination of Ca in biological systems. Indicator for the fluorimetric determination of calcium in presence of Mg by complexometric titration.

Purification Methods

Dissolve it in distilled H2O and acidify with dilute HCl to pH 3.5. Filter off the solid acid and wash it well with H2O. Redissolve ca 10g in 300mL H2O containing 12g of NaOAc. Precipitate it again by adding HCl, filtering and washing with H2O. Add the solid to 200mL of EtOH stir for 1hour and filter. Repeat the EtOH wash and dry the bright yellow solid in a vacuum. This acid decomposes on heating at ca 180o. See below for the preparation of the Na salt. [Diehl & Ellingboe Anal Chem 28 882 1956]. Altenatively dissolve it in H2O and acidify with 3N HCl to pH 3.5. Collect the solid and wash it with H2O. The air-dried precipitate is extracted with 70% aqueous EtOH, filtered hot and cooled slowly. Fine yellow needles of the acid crystallise out; they are filtered off and dissolved in the minimum quantity of 0.01N NaOH and re-precipitated by adding N HCl to pH 3.5. It is then recrystallised from 70% aqueous EtOH (3x). The final product (acid) is dried at 80o in a vacuum for 24hours, m >300o(dec). It contains one molecule of water per molecule of acid (C30H36N4O13.H2O). The product is pure as revealed by electrophoresis at pH 5.6 and 8.6, and by TLC in i-BuOH/i-PrOH/AcOH/H2O (60:60:5:5 by volume) or i-PrOH or pH 8.0 borate buffer. [Wallach et al. Anal Chem 31 456 1959.] The Na salt is prepared by dissolving the pure acid in H2O containing 2 mols of NaOH per mol of acid reagent and lyophilising. It complexes with Ca and Mg ions. [Beilstein 19 III/IV 4338.]

Fluorexon Preparation Products And Raw materials

Raw materials

Preparation Products

Fluorexon Suppliers

Global( 390)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Arnish Laborates Pvt Ltd +91 7208475595 Maharashtra, India 187 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
Esjay Chemicals +919820452929 Maharashtra, India 110 58 Inquiry
GSP Dyes and Chemicals Pvt.Ltd +91-22-28144802 +91-2228144802 Maharashtra, India 79 58 Inquiry
Anubhav Business Corporation +91-2228014519 +91-2228014999 Maharashtra, India 119 58 Inquiry
Grr Fine Chem/Grr Exports 91-79-40031771 Gujarat, India 405 58 Inquiry
ALPHA CHEMIKA 08048602756 Mumbai, India 76 58 Inquiry
S. Zhaveri Pharmakem Pvt. Ltd 91-22-43676666 Maharashtra, India 112 58 Inquiry
Pallav Chemicals & Solvents Pvt. Ltd. 91-22-49284000 Maharashtra, India 27 58 Inquiry
Oxford Laboratory 91-250-2390032 Maharashtra, India 43 58 Inquiry
Supplier Advantage
Arnish Laborates Pvt Ltd 58
JSK Chemicals 58
Esjay Chemicals 58
GSP Dyes and Chemicals Pvt.Ltd 58
Anubhav Business Corporation 58
Grr Fine Chem/Grr Exports 58
ALPHA CHEMIKA 58
S. Zhaveri Pharmakem Pvt. Ltd 58
Pallav Chemicals & Solvents Pvt. Ltd. 58
Oxford Laboratory 58

1461-15-0(Fluorexon)Related Search:

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AZOMETHINE H Fluorescein LIGNOSULFONIC ACID, CALCIUM SALT Fluorescein Sodium Benzophenone imine
CALCEIN-AM Folic acid Calcitonin salmon Citric acid Cellulose acetate
Ascoric Acid CALCEIN DISODIUM SALT, INDICATOR FOR COM PLEXOMETRY FLUORESCEIN-BIS-METHYLIMINODIACETIC ACID (SODIUM)
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BIS[N,N-BIS(CARBOXYMETHYL)AMINOMETHYL]FLUORESCEIN CALCEINE CALCEIN, INDICATOR FLUORESCEIN-2,7-BIS-METHYLIMINODIACETIC SODIUM SALT FLUORESCEIN COMPLEXON FLUORESCEIN COMPLEXONE FLUORESCEIN-METHYLENE-IMINODIACETIC ACID FLUOREXON FLUOREXONE FLUREXONE LABOTEST-BB LT00159821 2,7-BLS[BIS(CARBOXYMETHYL)AMINOMETHYL]-FLUORESCEIN 3,3'-BIS[N,N-BIS(CARBOXYMETHYL)AMINOMETHYL]FLUORESCEIN 3,6-DIHYDROXY-2,4-BIS-N,N'-DI-(CARBOXYMETHYL)-AMINOMETHYL FURAN FLUOREXON, INDICATOR GRADE CALCEIN INDICATOR FOR THE COMPLEXOMETRY CalceineIndicatorGr CalceineIndicatorGr(FluoresceinComplexone) CalceineIndicatorGr-(FluoresceinComplexon) FLUORESCEIN COMPLEXONE GR Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein~Fluorexon Oftasceine Glycine, N,N-(3,6-dihydroxy-3-oxospiroisobenzofuran-1(3H),9-9Hxanthene-2,7-diyl)bis(methylene)bisN-(carboxymethyl)- CALCEIN(RG) Fluorescein di-(methylimino diacetic acid) Calcein(Fluorexone) Calcein [for Fluorometric Determination of Ca] Fluorescein-bis(methyliminodiacetic acid), Fluorexon, Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein, Calcein, Fluorescein Complexon N,N'-[[3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-(carboxymethyl)glycine] Calcein,Bis[N,Nbis(carboxymethyl)aminomethyl]fluorescein, Fluorescein-bis(methyliminodiacetic acid), Fluorexon Calcein, indicator for metal titration Bis-[di(carboxyMethylaMinoMethyl)]flurescein sodiuM salt Fluorescein-2,7-bis-MethylaMinodiacetic acid sodiuM salt CALCEIN HYDRATE: FOR FLUOROMETRIC DETERMINATION OF CA CALCEIN INDICATOR FOR METAL DETERMINATIO 7’-diyl)bis(methylene)]bis[n-(carboxymethyl)--2 glycine,n,n’-[(3’,6’-dihydroxy-3-oxospiro[isobenzofuran-1(3h),9’-[9h]xanthene] N,N’-[(3’,6’-dihydroxy-3-oxospiro(isobenzofuran-1(3H),9’-(9H)xanthene)-2’,7’-diyl)bis(methyGlycine Fluorescein-bis(methyliminodiacetic acid) N,N'-[[3' oftasccine 2,2',2'',2'''-(((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-2',7'-diyl)bis(Methylene))bis(azanetriyl))tetraacetic acid Fluorescein, 2′,7′-bis[[bis(carboxymethyl)amino]methyl]- Spiro[isobenzofuran-1(3h),9′-[9h]xanthene], glycine deriv. 2,7-bis[n,n-bis(carboxymethyl)aminomethylene]- Uo-rescein Acetic acid, [(3′,6′-dihydroxy-2′,7′- Uorandiyl)bis-(methylenenitrilo)]tetra- Nsc 298193 Spiro[isobenzofuran-1(3h),9′-[9h]xanthene], glycine derivative Fluorescein, 2 0 ,7 0 -bis[[bis(carboxymethyl) amino]methyl]- Spiro[isobenzofuran-1(3 h ),9 0 -[9 h ]xanthene], Glycine derivative Acetic Acid, [(3 0 ,6 0 -dihydroxy-2 0 ,7 0 -fluor- andiyl)bis(methylenenitrilo)]tetra- Calcein indicator for metal determination Calcein, Suitable for fluorometric determination of calcium and EDTA titration of calcium in the presence of magnesium. Calcein, AR CALCEINCALCEINCALCEIN 3,3'-Bis[N,N-bis(carboxymethyl)aminomethyl]fluorescein (Calcein) Calcein, GR