ChemicalBook > Product Catalog >Biochemical Engineering >Biochemical Reagents >Acid-base indicator >α-Naphthoflavone
α-Naphthoflavone
- CAS No.
- 604-59-1
- Chemical Name:
- α-Naphthoflavone
- Synonyms
- BENZOFLAVONE;benzo(h)flavone;-Naphthoflavone;α-naphtoflavone;7,8-BENZOFLAVONE;à-naphthoflavone;A-NAPHTHOFLAVONE;1-Naphthoflavone;α-Naphthoflavone;a-Naphthylflavone
- CBNumber:
- CB0184955
- Molecular Formula:
- C19H12O2
- Molecular Weight:
- 272.3
- MOL File:
- 604-59-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/14 14:35:52
| Melting point | 153-157 °C (lit.) |
|---|---|
| Boiling point | 375.35°C (rough estimate) |
| Density | 1.1382 (rough estimate) |
| refractive index | 1.5510 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Crystalline Powder or Crystals |
| color | yellow |
| BRN | 210862 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| LogP | 5.003 (est) |
| CAS DataBase Reference | 604-59-1(CAS DataBase Reference) |
| EPA Substance Registry System | 4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl- (604-59-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H413 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P312-P330 | |||||||||
| Hazard Codes | Xi,Xn,C,F | |||||||||
| Risk Statements | 68-34-11 | |||||||||
| Safety Statements | 24/25-36/37-45-36/37/39-26-16 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QL6250000 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29143990 | |||||||||
| NFPA 704 |
|
α-Naphthoflavone price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N5757 | α-Naphthoflavone ≥98% | 604-59-1 | 1G | ₹4503.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N5757 | α-Naphthoflavone ≥98% | 604-59-1 | 5G | ₹5423.33 | 2022-06-14 | Buy |
| ALFA India | ALF-A18542-14 | alpha-Naphthoflavone, 97% | 604-59-1 | 25g | ₹25679 | 2022-05-26 | Buy |
| ALFA India | ALF-A18542-06 | alpha-Naphthoflavone, 97% | 604-59-1 | 5g | ₹5135 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B0056 | α-Naphthoflavone | 604-59-1 | 1G | ₹2000 | 2022-05-26 | Buy |
α-Naphthoflavone Chemical Properties,Uses,Production
Chemical Properties
yellow powder
Uses
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. α-Naphthoflavone is a flavone that modulates xenobiotic metabolism at several points. It antagonizes AhR, blocking the expression of phase I and II genes at nanomolar concentrations, although it can agonize AhR at higher concentrations (10 μM). α-Naphthoflavone inhibits CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50s = 500, 60, 6, and 5 nM, respectively), whereas it activates CYP3A4 (Kd = 7.4 μM). Dietary α-naphthoflavone can contribute to carcinogenesis in the presence of synthetic estrogens.[Cayman Chemical]
Definition
ChEBI: An extended flavonoid resulting from the formal fusion of a benzene ring with the h side of flavone. A synthetic compound, it is an inhibitor of aromatase (EC 1.14.14.14).
Purification Methods
Recrystallise the flavone from EtOH or aqueous EtOH. [IR: Cramer & Windel Chem Ber 89 354 1956, UV Pillon & Massicot Bull Soc Chim Fr 26 1954, Smith J Chem Soc 542
α-Naphthoflavone Preparation Products And Raw materials
Global( 289)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| PEE ESS AROMATICS | +919382160846 | Tamil Nadu, India | 53 | 58 | Inquiry |
| Dr. ASCRO Bio Sciences Private Limited | +undefined-7382260502 +undefined-+91 9182680914 | Telangana, India | 51 | 58 | Inquiry |
| CHEMAZON LABORATORIES | +91 9848551964 | Hyderabad, India | 1320 | 58 | Inquiry |
| AVIGYABIOSCIENCES PRIVATE LIMITED | +91-9849533087 +91-9849533087 | Telangana, India | 156 | 58 | Inquiry |
| S. Nihar Exports | 91 22 208 5632 | New Delhi, India | 232 | 50 | Inquiry |
| PEE ESS AROMATICS | +91 4426247322 | New Delhi, India | 258 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| PEE ESS AROMATICS | 58 |
| Dr. ASCRO Bio Sciences Private Limited | 58 |
| CHEMAZON LABORATORIES | 58 |
| AVIGYABIOSCIENCES PRIVATE LIMITED | 58 |
| S. Nihar Exports | 50 |
| PEE ESS AROMATICS | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| CHEMSWORTH | 30 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
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α-Naphthoflavone >
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Supply high quality Alpha-Naphthoflavone CAS 604-59-1 with fast delivery
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604-59-1
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