trans-Chalcone
- CAS No.
- 614-47-1
- Chemical Name:
- trans-Chalcone
- Synonyms
- (E)-CHALCONE;BENZALACETOPHENONE;cone;BENZYLIDENEACETOPHENONE;1,3-DIPHENYL-2-PROPEN-1-ONE;CHALKONE;1,3-DIPHENYL-2-PROPENONE;2-Propen-1-one, 1,3-diphenyl-, (E)-;Nsc167107;trans-ChaL
- CBNumber:
- CB7746253
- Molecular Formula:
- C15H12O
- Molecular Weight:
- 208.26
- MOL File:
- 614-47-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/3/3 9:06:10
| Melting point | 55-59 °C |
|---|---|
| Boiling point | 208 °C25 mm Hg(lit.) |
| Density | 1.0712 |
| refractive index | 1.5361 (estimate) |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Solid |
| color | Pale Yellow |
| Odor | at 100.00 %. floral balsam herbal |
| Odor Type | floral |
| Water Solubility | Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water. |
| Merck | 14,2037 |
| BRN | 509985 |
| LogP | 4.013 (est) |
| CAS DataBase Reference | 614-47-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzalacetophenone(614-47-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P301+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37 | |||||||||
| Safety Statements | 22-36/37/39-45 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UD5576750 | |||||||||
| HS Code | 29143990 | |||||||||
| NFPA 704 |
|
trans-Chalcone price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 136123 | trans-Chalcone 97% | 614-47-1 | 5G | ₹2067.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 136123 | trans-Chalcone 97% | 614-47-1 | 5G | ₹2067.58 | 2022-06-14 | Buy |
| Sigma-Aldrich | 136123 | trans-Chalcone 97% | 614-47-1 | 100G | ₹4611.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 136123 | trans-Chalcone 97% | 614-47-1 | 100G | ₹4611.45 | 2022-06-14 | Buy |
| ALFA India | ALF-A14734-36 | trans-Chalcone, 97% | 614-47-1 | 500g | ₹15835 | 2022-05-26 | Buy |
trans-Chalcone Chemical Properties,Uses,Production
Description
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Chemical Properties
Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.
Uses
trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.
Application
trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).
Preparation
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones
General Description
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Biological Activity
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Synthesis
Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.
trans-Chalcone Preparation Products And Raw materials
Raw materials
Preparation Products
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| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Sam Research Labs | 58 |
| Otto Chemie Pvt Ltd | 58 |
| Anubhav Business Corporation | 58 |
| Biosyn Research Chemicals | 58 |
| Clearsynth Labs | 58 |
| Reax Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Anubhav Business Corporation | 58 |
| Central Drug House(P) Ltd. | 58 |
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