4-Biphenylacetic acid
- CAS No.
- 5728-52-9
- Chemical Name:
- 4-Biphenylacetic acid
- Synonyms
- FELBINAC;Napageln;BIPHENYL-4-ACETIC ACID;[1,1'-BIPHENYL]-4-ACETIC ACID;2-([1,1'-biphenyl]-4-yl)acetic acid;L-141;TraxaM;LY-61017;Seltouch;CI 83544
- CBNumber:
- CB0186272
- Molecular Formula:
- C14H12O2
- Molecular Weight:
- 212.24
- MOL File:
- 5728-52-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/17 21:30:02
Melting point | 159-160 °C (lit.) |
---|---|
Boiling point | 312.08°C (rough estimate) |
Density | 1.1035 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO: soluble50mg/mL, clear, colorless to yellow |
pka | 4.29±0.10(Predicted) |
form | Powder |
color | Beige |
Water Solubility | 39.27mg/L(25 ºC) |
Merck | 14,3316 |
BRN | 1211592 |
InChI | InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) |
InChIKey | QRZAKQDHEVVFRX-UHFFFAOYSA-N |
SMILES | C1(C2=CC=CC=C2)=CC=C(CC(O)=O)C=C1 |
CAS DataBase Reference | 5728-52-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H301+H331-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P301+P310-P302+P352-P304+P340+P311-P305+P351+P338 | |||||||||
Hazard Codes | T,Xn | |||||||||
Risk Statements | 23/25-36/37/38-25-36/37/38/63-20/21/22 | |||||||||
Safety Statements | 26-36/37/39-45-37/39-28A-26/36/3745/60-20-36 | |||||||||
RIDADR | UN 2811 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DU8229050 | |||||||||
Hazard Note | Irritant | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29163900 | |||||||||
Toxicity | LD50 orally in rats: 164 mg/kg (Sloboda, Osterberg) | |||||||||
NFPA 704 |
|
4-Biphenylacetic acid price More Price(2)
4-Biphenylacetic acid Chemical Properties,Uses,Production
Description
Felbinac Is the active metabolite of the non-steroidal antiinflammatory agent, fenbufen. Applied topically as a gel to joints, it is useful in the symptomatic relief of articular inflammation and pain.
Chemical Properties
Off-white powder
Uses
4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug.
General Description
4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors.
Safety Profile
Poison by subcutaneous route.Moderately toxic by ingestion and intraperitoneal routes.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits acrid smoke and fumes.
4-Biphenylacetic acid Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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GMFC LABS PVT LTD | +91-9133370278 +91-9133370278 | Hyderabad, India | 44 | 58 | Inquiry |
AMINO ORGANICS | +919866989891 | Hyderabad, India | 275 | 58 | Inquiry |
ZCL Chemicals Ltd | +91-2261539999 +91-2261539999 | Maharashtra, India | 53 | 58 | Inquiry |
Stereokem Pvt Ltd | +91-4029706929 +91-9394224843 | Telangana, India | 350 | 58 | Inquiry |
SETV ASRV LLP | +91-9731133411 +91-9731133411 | Telangana, India | 531 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
Stereokem, Inc. | 500039 | New Delhi, India | 293 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Molkem Chemicals Pvt. Ltd. | 91-79-61202500 | Gujarat, India | 199 | 58 | Inquiry |
Supplier | Advantage |
---|---|
GMFC LABS PVT LTD | 58 |
AMINO ORGANICS | 58 |
ZCL Chemicals Ltd | 58 |
Stereokem Pvt Ltd | 58 |
SETV ASRV LLP | 58 |
CHEMSWORTH | 30 |
Stereokem, Inc. | 58 |
A.J Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
Molkem Chemicals Pvt. Ltd. | 58 |