Benzydamine hydrochloride
- CAS No.
- 132-69-4
- Chemical Name:
- Benzydamine hydrochloride
- Synonyms
- af864;tamas;verax;tantum;riripen;ririlim;indolin;imotryl;Afloben;Alcidol
- CBNumber:
- CB0204309
- Molecular Formula:
- C19H23N3O.ClH
- Molecular Weight:
- 345.87
- MOL File:
- 132-69-4.mol
- Modify Date:
- 2024/7/30 14:17:11
| Melting point | 147-153°C |
|---|---|
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water, ethanol, chloroform, n-butanol or DMSO /n |
| Merck | 14,1122 |
| InChIKey | HNNIWKQLJSNAEQ-UHFFFAOYSA-N |
| CAS DataBase Reference | 132-69-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NK7875000 | |||||||||
| HS Code | 2933.99.8290 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 110, 100 i.p.; 515, 1050 orally (Silvestrini) | |||||||||
| NFPA 704 |
|
Benzydamine hydrochloride price More Price(2)
Benzydamine hydrochloride Chemical Properties,Uses,Production
Description
Benzydamine hydrochloride is a non-steroidal antiinflammatory drug used both topically and systemically. It has been reported as a sensitizer and a photosensitizer and caused occupational contact dermatitis in a nurse.
Chemical Properties
Off-White Solid
Uses
Benzydamine hydrochloride is an anti-in-flammatory drug used extensively in Europe and recently introduced in Canada to help re duce painful mucositis. Benzydamine provides short-term topical anesthesia and extended pain relief apparently through its anti-inflammatory properties. Studies have shown it to be effective in a range of painful conditions, including aphthous ulceration, chemotherapy-induced mucositis, and radiation-induced mucositis.
Contact allergens
It is a nonsteroidal anti-inflammatory drug used both topically and systemically. It has been reported as a sensitizer and a photosensitizer.
Side effects
The major side effects of benzydamine hydrochloride are oral numbness (reported prevalence: 10 percent), and oral burning/stinging (reported prevalence: 8 percent). Oral discomfort appears to be more of a problem in patients with extensive ulceration/infammation. The oral discomfort can sometimes be improved by diluting the benzydamine hydrochloride with an equal volume of water.It is thought that benzydamine hydrochloride does not precipitate peptic ulceration.
Safety Profile
Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental animal reproductive effects. An eye irritant. A nonsteroidal antiinflammatory analgesic. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Benzydamine hydrochloride Preparation Products And Raw materials
Raw materials
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| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
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