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ChemicalBook > Product Catalog >API >Synthetic Anti-infective Drugs >Sulfonamides and synergist >(S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide Structure
CAS No.
343338-28-3
Chemical Name:
(S)-(-)-2-Methyl-2-propanesulfinamide
Synonyms
(S)-2-METHYLPROPANE-2-SULFINAMIDE;TERT-BUTYL SULFINAMIDE;(S)-(-)-T-BUTYLSULFINAMIDE;S-BSN;finamide;Suprabasin;S-tert-butylsulfonamide;S- tert butyl sulfenaMide;Brilanestrant Impurity 10;(S)-(-)-TERT-BUTYLSULFINAMIDE
CBNumber:
CB0209955
Molecular Formula:
C4H11NOS
Molecular Weight:
121.2
MOL File:
343338-28-3.mol
MSDS File:
SDS
Modify Date:
2024/8/6 16:32:36
Request For Quotation

(S)-(-)-2-Methyl-2-propanesulfinamide Properties

Melting point 97-101 °C(lit.)
alpha -4.5 º (c=1, CHCl3)
Boiling point 220.0±23.0 °C(Predicted)
Density 1.124
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 10.11±0.50(Predicted)
form Crystalline Powder
color White
optical activity [α]20/D 4.5°, c = 1 in chloroform
Stability store cold
InChI InChI=1/C4H11NOS/c1-4(2,3)7(5)6/h5H2,1-3H3/t7-/s3
InChIKey CESUXLKAADQNTB-SSDOTTSWSA-N
SMILES CC(C)([S@@](N)=O)C |&1:3,r|
CAS DataBase Reference 343338-28-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338-P304+P340-P405-P501A
Hazard Codes  Xi,Xn,F
Risk Statements  11-19-36/37-40
Safety Statements  16-26-36/37-24/25
WGK Germany  3
Hazard Note  Irritant/Keep Cold
TSCA  No
HS Code  29309090
NFPA 704
1
1 0

(S)-(-)-2-Methyl-2-propanesulfinamide price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 513210 (S)-(−)-2-Methyl-2-propanesulfinamide 97% 343338-28-3 1G ₹6408.4 2022-06-14 Buy
Sigma-Aldrich(India) 513210 (S)-(−)-2-Methyl-2-propanesulfinamide 97% 343338-28-3 5G ₹19647.38 2022-06-14 Buy
Sigma-Aldrich(India) 513210 (S)-(−)-2-Methyl-2-propanesulfinamide 97% 343338-28-3 25G ₹61269.5 2022-06-14 Buy
TCI Chemicals (India) B2908 (S)-(-)-tert-Butylsulfinamide min. 98.0 % 343338-28-3 1G ₹2000 2022-05-26 Buy
TCI Chemicals (India) B2908 (S)-(-)-tert-Butylsulfinamide min. 98.0 % 343338-28-3 5G ₹5500 2022-05-26 Buy
Product number Packaging Price Buy
513210 1G ₹6408.4 Buy
513210 5G ₹19647.38 Buy
513210 25G ₹61269.5 Buy
B2908 1G ₹2000 Buy
B2908 5G ₹5500 Buy

(S)-(-)-2-Methyl-2-propanesulfinamide Chemical Properties,Uses,Production

Physical properties

white to light yellow crystal powder

Uses

(S)-(-)-2-Methyl-2-propanesulfinamide is used in Suzuki reaction. It is also employed as a reagent for synthesizing chiral amines. It acts as a chiral auxiliary used in an asymmetric synthesis of trifluoroethylamines by conversion of trifluoroacetaldehyde to a chiral imine. It is also involved in the transformation of P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. Further, it serves as a reagent for the preparation of chemicals and pharmaceutical intermediates.

Uses

(S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. It may also be used to prepare (20E)-N-[t-butyl-(S)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the preparation of androgen receptor antagonists.

(S)-(-)-2-Methyl-2-propanesulfinamide Preparation Products And Raw materials

Raw materials

Preparation Products

(S,E)-N-(2-(tert-butyldimethylsilyloxy)ethylidene)-2-methylpropane-2-sulfinamide 2-Propanesulfinamide, N-(4-chlorobutylidene)-2-methyl-, [N(E),S(S)]- (2S,3R,SS)-2-(tert-butylsulfinamido)-3-methylpent-4-enoic acid

(S)-(-)-2-Methyl-2-propanesulfinamide Suppliers

Global( 452)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Biosyn Research Chemicals +91-91-9346022300 +91-9346022300 Telangana, India 465 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Spectrochem Private Limited 08048372608Ext 246 Maharashtra, India 1056 58 Inquiry
VASIN BIO LIFE SCIENCES PVT LTD 9491644688 Hyderabad, India 2096 58 Inquiry
Biosyn Research Chemicals +91 9346022300/+91 9399339999 Telangana, India 1340 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
Supplier Advantage
Biosyn Research Chemicals 58
JSK Chemicals 58
CHEMSWORTH 30
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Alfa Aesar 58
Spectrochem Private Limited 58
VASIN BIO LIFE SCIENCES PVT LTD 58
Biosyn Research Chemicals 58
Reax Chemicals 58

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(R)-4-Benzyl-2-oxazolidinone (S)-4-Benzyl-2-oxazolidinone (S)-(+)-4-Phenyl-2-oxazolidinone Di-tert-butylphosphine Tri-tert-butylphosphine
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2-METHYL-2-PROPANE-SULFINAMIDE(S-ISOMER) (S)-tert-Butylsulfinamide, (>98.0% ee), 97+% (S)-(-)-2-METHYL-2-PROPANESULPHINAMIDE (S)-(-)-2-METHYL-PROPANE-2-SULFINIC ACID AMIDE (S)-(-)-TERT-BUTYLSULFINAMIDE (S)-(-)-TERT-BUTYL SULPHINAMIDE (S)-(-)-T-BUTYLMETHYLSULFINAMIDE (S)-(-)-2-Methylpropane-2-sulphinamide 98% [S(S)]-2-Methyl-2-propanesulfinaMide 2-PropanesulfinaMide, 2-Methyl-, [S(S)]- S-BSN S- tert butyl sulfenaMide (S)-tert-Butylsulfinamide (S)-(-)-2-Methyl-2-propanesulfinamide (S)-(?)-2-Methyl-2-propanesulfinamide solution ANTI-SBSN (N-TERM) antibody produced in rabbit Suprabasin (S)-(-)-tert-Butylsulfinamide (S)-(-)-2-Methyl-2-propanesulfinamide 97% Amino(tert-butyl)sulfaniumolate (S)-(-)-2-Methyl-2-propanesulfimide (S)-2-Methyl-2-propanesulfinamide,99%e.e. (S)-(-)-t-Butylmethylsulfinamide,min.97% (S)-(-)-tert-Butyl sulphinamide 98% (S)-(-)-t-Butyl sulfinamide, 98% ee (S)-TERT-BUTANESULFINAMIDE / (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE (S)-(-)-2-METHYL-2-PROPANESULFINAMIDE,98.5+% (S)-TERT-BUTYLSULFINAMIDE,97+% (>98.0% EE) (S)-(-)-t-Butylmethylsulfinamide, min. 97% (S)-tert-Butylsulfinamide, (>98.0% ee) (S)-(-)-2-Methyl-2-propanesulfinamide (S)-(-)-t-Butylsulfinamide, min. 97% (S)-TERT-BUTANESULFINAMIDE / (S)-(-)-2-METHYL-2-P S-tert-butylsulfonamide (S)-Tert butane sulfonamide 98% (S)-(-)-2-Methyl-2-propanesulfinaMide(S)-(-)-2-Methyl-2-propanesulfinaMide finamide (S)-(-)-tert-Butylsulfinamide > (S)-(-)-tert-Butylsulfinamide, 98%, for synthesis (S)-(-)-2-Methyl-2-propanesulfinamide USP/EP/BP (S)-2-METHYLPROPANE-2-SULFINAMIDE (S)-(-)-T-BUTYLSULFINAMIDE TERT-BUTYL SULFINAMIDE Brilanestrant Impurity 10 343338-28-3 343338-27-8 3423338-28-3 343338-28-2 C3H11CNOS C4H9CH3SONH2 C4H11NOS Organic Building Blocks Sulfur-Based Sulfur Compounds Sulfonamides/Sulfinamides Building Blocks Asymmetric Synthesis Chiral Auxiliaries Asymmetric Synthesis