Ciprofloxacin HCl

Ciprofloxacin HCl Structure
CAS No.
93107-08-5
Chemical Name:
Ciprofloxacin HCl
Synonyms
CIPROFLOXACIN HYDROCHLORIDE;1-Cyclopropyl-6-fluoro;1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride;Cyproxan;BAY-o-9867;CIPROFLOXACIN HCL;Bay-09867 (hydrochloride);Clprofloxacin hydrochloride;Ciprofloxacin hydrochloride CAS 93107-08-5
CBNumber:
CB02130396
Molecular Formula:
C17H18FN3O3.HCl
Molecular Weight:
367.8
MOL File:
93107-08-5.mol
MSDS File:
SDS
Modify Date:
2024/7/4 14:04:14

Ciprofloxacin HCl Properties

Melting point >300 ºC
storage temp. Sealed in dry,Room Temperature
solubility insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic
form crystalline solid
color White to off-white
BCS Class 3
InChI InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
InChIKey DIOIOSKKIYDRIQ-UHFFFAOYSA-N
SMILES O=C(O)C1C(=O)C2=CC(=C(C=C2N(C2CC2)C=1)N1CCNCC1)F.[H]Cl
CAS DataBase Reference 93107-08-5

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
HS Code  29339900

Ciprofloxacin HCl Chemical Properties,Uses,Production

Uses

Anti-bacterial

brand name

Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).

Synthesis

The preparation method of ciprofloxacin HCl, its step is as follows:
a) cyclopropyl carboxylic acid is added in the organic solvent, and the adding piperazine, reacted 3~8 hours down as acid binding agent with alkali at 60~120 ℃, the monitoring cyclopropyl carboxylic acid is residual less than 2% o'clock termination reaction, stirring is cooled to 0~30 ℃, leaves standstill suction filtration;
b) add water and hydrochloric acid in the products therefrom toward a) step, under agitation be warming up to molten clearly, add activated carbon decolorizing, filtered while hot, and transfer filtrate pH to 2~4 with hydrochloric acid, and the cooling crystallization filters, rinsing, and drying makes ciprofloxacin HCl.

Ciprofloxacin HCl Preparation Products And Raw materials

Global( 263)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SKVNTTR LIFE SCIENCE LLP +91-9825953518 +91-9825953518 Gujarat, India 9 58 Inquiry
Aurobindo Pharma Limited +914066725000 Telangana, India 112 58 Inquiry
Sun Pharmaceutical Industries Ltd +91-2242244224 +91-2243244324 Maharashtra, India 108 58 Inquiry
Smruthi Organics Limited +91-9881467770 +91-9822910599 Maharashtra, India 24 58 Inquiry
HRV Global Life Sciences +91-9820219686 +91-9820219686 Telangana, India 379 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) +91-1142631798 +91-9899000024 New Delhi, India 55 58 Inquiry
Aarti Drugs Ltd (part of Aarti Group of Industries) +91-2224019025 +91-9136988221 Maharashtra, India 57 58 Inquiry
J.B. Chemicals Pharmaceuticals Ltd. +91-022-24822222 +91-02224822222 Mumbai, India 10 58 Inquiry
Sreepathi Pharmaceuticals Limited +91-9848883324 +91-9848883318 Telangana, India 13 58 Inquiry

Ciprofloxacin HCl Spectrum

3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1) BAY-o-9867 Cyproxan 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride Clprofloxacin hydrochloride 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride CIPROFLOXACIN HCL Ciprofloxacin hydrochloride CAS 93107-08-5 Bay-09867 (hydrochloride) Enrofloxacin EP Impurity BQ: What is Enrofloxacin EP Impurity B Q: What is the CAS Number of Enrofloxacin EP Impurity B 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride CIPROFLOXACIN HYDROCHLORIDE 1-Cyclopropyl-6-fluoro Bay-09867 (hydrochloride)|||Ciprofloxacin HCl|||Ciprofloxacin hydrochloride 93107-08-5 C17H19ClFN3O3xHCl Pharmaceutical intermediate 93107-08-5