Ciprofloxacin HCl
![Ciprofloxacin HCl Structure](CAS/GIF/93107-08-5.gif)
- CAS No.
- 93107-08-5
- Chemical Name:
- Ciprofloxacin HCl
- Synonyms
- CIPROFLOXACIN HYDROCHLORIDE;1-Cyclopropyl-6-fluoro;1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride;Cyproxan;BAY-o-9867;CIPROFLOXACIN HCL;Bay-09867 (hydrochloride);Clprofloxacin hydrochloride;Ciprofloxacin hydrochloride CAS 93107-08-5
- CBNumber:
- CB02130396
- Molecular Formula:
- C17H18FN3O3.HCl
- Molecular Weight:
- 367.8
- MOL File:
- 93107-08-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/4 14:04:14
Melting point | >300 ºC |
---|---|
storage temp. | Sealed in dry,Room Temperature |
solubility | insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic |
form | crystalline solid |
color | White to off-white |
BCS Class | 3 |
InChI | InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H |
InChIKey | DIOIOSKKIYDRIQ-UHFFFAOYSA-N |
SMILES | O=C(O)C1C(=O)C2=CC(=C(C=C2N(C2CC2)C=1)N1CCNCC1)F.[H]Cl |
CAS DataBase Reference | 93107-08-5 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Safety Statements | 24/25 |
HS Code | 29339900 |
Ciprofloxacin HCl Chemical Properties,Uses,Production
Uses
Anti-bacterial
brand name
Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).
Synthesis
The preparation method of ciprofloxacin HCl, its step is as follows:
a) cyclopropyl carboxylic acid is added in the organic solvent, and the adding piperazine, reacted 3~8 hours down as acid binding agent with alkali at 60~120 ℃, the monitoring cyclopropyl carboxylic acid is residual less than 2% o'clock termination reaction, stirring is cooled to 0~30 ℃, leaves standstill suction filtration;
b) add water and hydrochloric acid in the products therefrom toward a) step, under agitation be warming up to molten clearly, add activated carbon decolorizing, filtered while hot, and transfer filtrate pH to 2~4 with hydrochloric acid, and the cooling crystallization filters, rinsing, and drying makes ciprofloxacin HCl.
Ciprofloxacin HCl Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
SKVNTTR LIFE SCIENCE LLP | +91-9825953518 +91-9825953518 | Gujarat, India | 9 | 58 | Inquiry |
Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
Smruthi Organics Limited | +91-9881467770 +91-9822910599 | Maharashtra, India | 24 | 58 | Inquiry |
HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) | +91-1142631798 +91-9899000024 | New Delhi, India | 55 | 58 | Inquiry |
Aarti Drugs Ltd (part of Aarti Group of Industries) | +91-2224019025 +91-9136988221 | Maharashtra, India | 57 | 58 | Inquiry |
J.B. Chemicals Pharmaceuticals Ltd. | +91-022-24822222 +91-02224822222 | Mumbai, India | 10 | 58 | Inquiry |
Sreepathi Pharmaceuticals Limited | +91-9848883324 +91-9848883318 | Telangana, India | 13 | 58 | Inquiry |