2-Amino-6-chloro-3-nitropyridine
![2-Amino-6-chloro-3-nitropyridine Structure](CAS/GIF/27048-04-0.gif)
- CAS No.
- 27048-04-0
- Chemical Name:
- 2-Amino-6-chloro-3-nitropyridine
- Synonyms
- 6-CHLORO-3-NITROPYRIDIN-2-AMINE;LABOTEST-BB LT00012599;2-Amino-6-chloro-3-nitrop...;2-amino-3-nitrochloropyridine;6-Chlor-3-nitropyridin-2-amin;2-Amino-3-nitro-6-chloropyridi;2-Amino-6-chlor-3-nitropyridin;2-Amino-6-chloro-nitro pyridne;FlupirtinemaleateintermediateI;6-Chloro-3-nitro-2-pyridinamine
- CBNumber:
- CB0245762
- Molecular Formula:
- C5H4ClN3O2
- Molecular Weight:
- 173.56
- MOL File:
- 27048-04-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/9/3 18:36:42
Melting point | 195-196 |
---|---|
Boiling point | 339.9±37.0 °C(Predicted) |
Density | 1.596±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | Chloroform, DMSO |
form | Crystalline |
pka | -1.69±0.50(Predicted) |
color | Yellow |
Water Solubility | Slightly soluble in water. Soluble in dimethyl sulfoxide and chloroform. |
InChI | InChI=1S/C5H4ClN3O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H,(H2,7,8) |
InChIKey | WERABQRUGJIMKQ-UHFFFAOYSA-N |
SMILES | C1(N)=NC(Cl)=CC=C1[N+]([O-])=O |
CAS DataBase Reference | 27048-04-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H312-H315-H319-H331-H335 | |||||||||
Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 22-26-36/37/39 | |||||||||
RIDADR | 2811 | |||||||||
Hazard Note | Irritant | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | Ⅲ | |||||||||
HS Code | 29333999 | |||||||||
NFPA 704 |
|
2-Amino-6-chloro-3-nitropyridine price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemicals (India) | A1756 | 2-Amino-6-chloro-3-nitropyridine min. 98.0 % | 27048-04-0 | 5G | ₹2100 | 2022-05-26 | Buy |
TCI Chemicals (India) | A1756 | 2-Amino-6-chloro-3-nitropyridine min. 98.0 % | 27048-04-0 | 25G | ₹4500 | 2022-05-26 | Buy |
ALFA India | ALF-H64634-22 | 2-Amino-6-chloro-3-nitropyridine, 98% | 27048-04-0 | 100g | ₹11511 | 2022-05-26 | Buy |
ALFA India | ALF-H64634-14 | 2-Amino-6-chloro-3-nitropyridine, 98% | 27048-04-0 | 25g | ₹2883 | 2022-05-26 | Buy |
2-Amino-6-chloro-3-nitropyridine Chemical Properties,Uses,Production
Description
2-Amino-6-chloro-3-nitropyridine is a cytotoxic drug that has been shown to have anti-viral potency, as well as antiviral activity in an activity test. It is synthesized by reacting hydrogen tartrate with oxadiazole, and then hydrolyzing the resulting product with chloride. 2-Amino-6-chloro-3-nitropyridine has also been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in vitro and to be effective against other viruses such as type 2 influenza. This drug can bind to the viral envelope and inhibit fusion of the viral membrane with host cells by preventing the release of viral contents into the cytoplasm. The binding affinity of 2-amino 6-chloro 3 nitropyridine for chloride may be due to hydrogen bonding interactions.
Chemical Properties
YELLOW POWDER
Uses
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Synthesis
The 2-Amino-6-chloro-3-nitropyridine may be obtained by the ammonolysis of 2,6-dichloro-3-nitropyridine by a known process. The ammonolysis is carried out by using solution of aqueous ammonia in methanol at 35°–40° C. After the reaction is over, the product is obtained by filtration.
2-Amino-6-chloro-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Advantage |
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GLR Innovations | 58 |
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED | 58 |
SYNIX LABS | 58 |
Vijayasai Lifesciences | 58 |
SRINIVASA LABS | 58 |
Varna Chems | 58 |
SVH BIOSCIENCES | 58 |
CHATURYA BIOTECH | 58 |
VGS SYNTHESIS PRIVATE LIMITED | 58 |
Aastrid Life Sciences Private Limited | 58 |
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