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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Chloropyridine >2-Amino-6-chloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine

2-Amino-6-chloro-3-nitropyridine Structure
CAS No.
27048-04-0
Chemical Name:
2-Amino-6-chloro-3-nitropyridine
Synonyms
6-CHLORO-3-NITROPYRIDIN-2-AMINE;LABOTEST-BB LT00012599;2-Amino-6-chloro-3-nitrop...;2-amino-3-nitrochloropyridine;6-Chlor-3-nitropyridin-2-amin;2-Amino-3-nitro-6-chloropyridi;2-Amino-6-chlor-3-nitropyridin;2-Amino-6-chloro-nitro pyridne;FlupirtinemaleateintermediateI;6-Chloro-3-nitro-2-pyridinamine
CBNumber:
CB0245762
Molecular Formula:
C5H4ClN3O2
Molecular Weight:
173.56
MOL File:
27048-04-0.mol
MSDS File:
SDS
Modify Date:
2024/9/3 18:36:42
Request For Quotation

2-Amino-6-chloro-3-nitropyridine Properties

Melting point 195-196
Boiling point 339.9±37.0 °C(Predicted)
Density 1.596±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform, DMSO
form Crystalline
pka -1.69±0.50(Predicted)
color Yellow
Water Solubility Slightly soluble in water. Soluble in dimethyl sulfoxide and chloroform.
InChI InChI=1S/C5H4ClN3O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H,(H2,7,8)
InChIKey WERABQRUGJIMKQ-UHFFFAOYSA-N
SMILES C1(N)=NC(Cl)=CC=C1[N+]([O-])=O
CAS DataBase Reference 27048-04-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H331-H335
Precautionary statements  P261-P280-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-26-36/37/39
RIDADR  2811
Hazard Note  Irritant
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  29333999
NFPA 704
0
2 0

2-Amino-6-chloro-3-nitropyridine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) A1756 2-Amino-6-chloro-3-nitropyridine min. 98.0 % 27048-04-0 5G ₹2100 2022-05-26 Buy
TCI Chemicals (India) A1756 2-Amino-6-chloro-3-nitropyridine min. 98.0 % 27048-04-0 25G ₹4500 2022-05-26 Buy
ALFA India ALF-H64634-22 2-Amino-6-chloro-3-nitropyridine, 98% 27048-04-0 100g ₹11511 2022-05-26 Buy
ALFA India ALF-H64634-14 2-Amino-6-chloro-3-nitropyridine, 98% 27048-04-0 25g ₹2883 2022-05-26 Buy
Product number Packaging Price Buy
A1756 5G ₹2100 Buy
A1756 25G ₹4500 Buy
ALF-H64634-22 100g ₹11511 Buy
ALF-H64634-14 25g ₹2883 Buy

2-Amino-6-chloro-3-nitropyridine Chemical Properties,Uses,Production

Description

2-Amino-6-chloro-3-nitropyridine is a cytotoxic drug that has been shown to have anti-viral potency, as well as antiviral activity in an activity test. It is synthesized by reacting hydrogen tartrate with oxadiazole, and then hydrolyzing the resulting product with chloride. 2-Amino-6-chloro-3-nitropyridine has also been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in vitro and to be effective against other viruses such as type 2 influenza. This drug can bind to the viral envelope and inhibit fusion of the viral membrane with host cells by preventing the release of viral contents into the cytoplasm. The binding affinity of 2-amino 6-chloro 3 nitropyridine for chloride may be due to hydrogen bonding interactions.

Chemical Properties

YELLOW POWDER

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Synthesis

The 2-Amino-6-chloro-3-nitropyridine may be obtained by the ammonolysis of 2,6-dichloro-3-nitropyridine by a known process. The ammonolysis is carried out by using solution of aqueous ammonia in methanol at 35°–40° C. After the reaction is over, the product is obtained by filtration.

2-Amino-6-chloro-3-nitropyridine Preparation Products And Raw materials

Raw materials

2(1H)-Pyridinone, 6-amino-5-nitro- 2-Chloro-6-methoxy-3-nitropyridine 2,6-Dichloro-3-nitropyridine 2-Amino-6-methoxy-3-nitropyridine 2,6-Dichloropyridine

Preparation Products

Flupirtine 6-Chloro-2,3-diaminopyridine 2,3-DIAMINO-6-CHLOROPYRIDINE N-(6-CHLORO-3-NITROPYRIDIN-2-YL)ACETAMIDE TERT-BUTYL CARBAZATE
2-Amino-5-nitropyridine 2-Chloro-5-nitropyridin-4-amine 2-Chloro-5-nitropyridine 6-BROMOPYRIDINE-2,3-DIAMINE 2-AMino-6-(benzylaMino)-3-nitropyridine
(5-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)methanol 5-broMo-6-ethoxy-3-nitropyridin-2-aMine
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Supplier Advantage
GLR Innovations 58
ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED 58
SYNIX LABS 58
Vijayasai Lifesciences 58
SRINIVASA LABS 58
Varna Chems 58
SVH BIOSCIENCES 58
CHATURYA BIOTECH 58
VGS SYNTHESIS PRIVATE LIMITED 58
Aastrid Life Sciences Private Limited 58

2-Amino-6-chloro-3-nitropyridine Spectrum

2-Amino-6-chloro-3-nitropyridine(27048-04-0)1HNMR2-Amino-6-chloro-3-nitropyridine(27048-04-0)FT-IR

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2-AMINO-6-CHLORO-3-NITROPYRIDINE 2-AMINO-3-NITRO-6-CHLOROPYRIDINE 6-chloro-3-nitropyridin-2-ylamine 2-amino-3-nitrochloropyridine 2-AMINO-6-CHLOR-3-NITROPYRIDIN 95% 2-Amino-3-nitro-6-chloropyridi 2-Amino-6-chloro-3-nitropyridine 98% LABOTEST-BB LT00012599 6-Amino-2-chloro-5-nitropyridine 6-Chloro-3-nitro-2-pyridinamine 2-Amino-3-nitro-6-chloropyridine ,98% 6-Chloro-3-nitropyridine-2-amine 2-Amino-6-chloro-3-nitropyridine,97% 6-Chloro-3-nitro-2-pyridylamine 2-Amino-6-chloro-3-nitrop... 2-Amino-6-chlor-3-nitropyridin 2-Pyridinamine, 6-chloro, 3-nitro- 2-AMINO-6-CHLORO-3-NITROYRIDINE 2-AMine-3-nitro-6-chloropyridine 2-AMINO-6-CHOLORO-3-NITRO PYRIDINE ( RE- EXPORT SHIPMENT ) 2-Amino-6-chloro-nitro pyridne FlupirtinemaleateintermediateI 6-Chlor-3-nitropyridin-2-amin 2-Amino-6-chloro-3-nitropyridine ISO 9001：2015 REACH 2-amino-3-nitro-6-chloropyridineQ: What is 2-amino-3-nitro-6-chloropyridine Q: What is the CAS Number of 2-amino-3-nitro-6-chloropyridine Q: What is the storage condition of 2-amino-3-nitro-6-chloropyridine Q: What are the applications of 2-amino-3-nitro-6-chloropyridine 6-CHLORO-3-NITROPYRIDIN-2-AMINE 6-Chloro-3-nitro pyridine-2-ylamine 6-Chlor-3-nitropyridin-2-ylamin 27048-04-0 C5H4CIN2O2 Aromatics Heterocycles Miscellaneous Reagents Pyridines Pyridine pyridine derivative Amines blocks NitroCompounds