Pamoic acid disodium salt
![Pamoic acid disodium salt Structure](CAS/GIF/6640-22-8.gif)
- CAS No.
- 6640-22-8
- Chemical Name:
- Pamoic acid disodium salt
- Synonyms
- PAMOIC ACID NA;sodium pamoate;DISODIUMEMBONATE;DisodiumPamoate98%;PAMOIC ACID DISODIUM;Cyprofuram Impurity 1;PAMOIC ACID DISODIUM SALT;EMBONIC ACID DISODIUM SALT;PAMOIC ACID DISODIUM SALT 98%;PAMOIC ACID DISODIUM SALT 98+%
- CBNumber:
- CB0247382
- Molecular Formula:
- C23H17NaO6
- Molecular Weight:
- 412.37
- MOL File:
- 6640-22-8.mol
- Modify Date:
- 2023/6/8 17:06:33
Melting point | 300 °C |
---|---|
Density | 1.55[at 20℃] |
vapor pressure | 0.001Pa at 25℃ |
storage temp. | Desiccate at RT |
solubility | insoluble in EtOH; ≥18 mg/mL in H2O; ≥28.6 mg/mL in DMSO |
form | solid |
color | Pale yellow |
Water Solubility | 43g/L at 20℃ |
LogP | -3.2 at 20℃ |
CAS DataBase Reference | 6640-22-8(CAS DataBase Reference) |
EPA Substance Registry System | 2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy-, disodium salt (6640-22-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 20/21/22-37/38-41-48 | |||||||||
Safety Statements | 24/25-45-36/37/39-26-22 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2918.29.7500 | |||||||||
NFPA 704 |
|
Pamoic acid disodium salt price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P5022 | Pamoic acid disodium salt | 6640-22-8 | 25G | ₹7231.1 | 2022-06-14 | Buy |
TCI Chemicals (India) | P1059 | Pamoic Acid Disodium Salt Monohydrate | 6640-22-8 | 25G | ₹3600 | 2022-05-26 | Buy |
TCI Chemicals (India) | P1059 | Pamoic Acid Disodium Salt Monohydrate | 6640-22-8 | 250G | ₹20800 | 2022-05-26 | Buy |
Pamoic acid disodium salt Chemical Properties,Uses,Production
Chemical Properties
pale yellow to yellow powder
Uses
Pamoic acid disodium salt, a supposedly inactive component in many formulations of drugs used to modulate release, is a potent agonist of the orphan receptor GPR35. GPR35 is a class A, rhodopsin-like G protein-coupled receptor (GPCR), strongly expressed in the lower intestine and colon, dorsal root ganglia, as well as a variety of immune cells including monocytes and dendritic cells. Targeting GPR35 provides potential therapeutic opportunities in a range of conditions, such as inflammation, pain and cancer.
Biological Activity
Pamoic acid disodium salt is a GPR35 agonist. Induces GPR35 internalization and activates ERK1/2 (EC50 values are 22 and 65 nM respectively). Mediates recruitment of β-arrestin2 to GPR35. Also exhibits antinociceptive effects in a mouse model of visceral pain.
Pamoic acid disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
LAIRUS PHARMA PVTLTD | +91-7517039862 +91-7517039862 | Maharashtra, India | 25 | 58 | Inquiry |
Horizon | +91-7517039862 +91-7517039862 | Maharashtra, India | 36 | 58 | Inquiry |
Ramdev Chemicals Pvt Ltd | +91-9320010324 +91-9320010323 | Maharashtra, India | 16 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Globe Chemie | 08048372441Ext 581 | Pune, India | 101 | 58 | Inquiry |
Ramdev Chemicals Pvt., Ltd. | 91-22-62105000 | Maharashtra, India | 9 | 58 | Inquiry |
Halcyon Labs Pvt. Ltd. | 08048250466Ext 769 | Ahmedabad, India | 12 | 58 | Inquiry |
Supplier | Advantage |
---|---|
SNECOFRi Pvt Ltd | 58 |
LAIRUS PHARMA PVTLTD | 58 |
Horizon | 58 |
Ramdev Chemicals Pvt Ltd | 58 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Globe Chemie | 58 |
Ramdev Chemicals Pvt., Ltd. | 58 |
Halcyon Labs Pvt. Ltd. | 58 |
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