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Torezolid

Torezolid Structure
CAS No.
856866-72-3
Chemical Name:
Torezolid
Synonyms
Tedizolid;(R)-3-(3-fluoro-4-(6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxyMethyl)oxazolidin-2-one;Tedizolidted;CS-1826;Tedizolid Impurity 47;DA-7157;DA 7157;Torezolid;Torezolid-21;Torezolid (TR-701
CBNumber:
CB02484972
Molecular Formula:
C17H15FN6O3
Molecular Weight:
370.34
MOL File:
856866-72-3.mol
Modify Date:
2024/7/5 11:27:04
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Torezolid Properties

Melting point 201 °C
Boiling point 614.5±65.0 °C(Predicted)
Density 1.57
storage temp. Refrigerator
solubility DMSO (Slightly, Heated), Water (Slightly, Heated)
form Solid
pka 14.05±0.10(Predicted)
color White to Off-White
InChI InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1
InChIKey XFALPSLJIHVRKE-GFCCVEGCSA-N
SMILES O1[C@@H](CO)CN(C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2)C1=O
CAS DataBase Reference 856866-72-3

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361-H373
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P260-P314-P501
HS Code  29339900

Torezolid Chemical Properties,Uses,Production

Uses

Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.

Definition

ChEBI: A member of the class of pyridines that is pyridine which is substituted by a 2-methyl-2H-tetrazol-5-yl group at position 2 and by a 2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl group at position 5 It is used as its phosphate pro-drug used for the treatment of acute bacterial skin and skin structure infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and meth cillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.

Torezolid Preparation Products And Raw materials

Raw materials

(5R)-3-(4-BROMO-3-FLUOROPHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE 5-BROMO-2-(2-METHYL-2H-TETRAZOL-5-YL)-PYRIDINE 2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine (R)-3-(3-FLUOROPHENYL)-5-(HYDROXYMETHYL)OXAZOLIDIN-2-ONE (5R)-3-(3-FLUORO-4-IODOPHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE
Benzyl (4-broMo-3-fluorophenyl)carbaMate (R)-Glycidyl butyrate CarbaMic acid, N-[3-fluoro-4-[6-(2-Methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-, phenylMethyl ester 2,5-Dibromopyridine 3-Fluoroaniline
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Preparation Products

Torezolid Suppliers

Global( 262)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Lupin Ltd +91-8019896181 +91-8019896181 Maharashtra, India 93 58 Inquiry
Honour Lab Limited +919845977466 Telangana, India 164 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Jigs Chemical Limited +91 80 4290 2764 Ahmedabad, India 235 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +8613288715578 China 12456 58 Inquiry
Hangzhou Hyper Chemicals Limited +86-0086-57187702781 +8613675893055 China 230 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Supplier Advantage
Lupin Ltd 58
Honour Lab Limited 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Jigs Chemical Limited 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Hebei Mojin Biotechnology Co., Ltd 58
Hangzhou Hyper Chemicals Limited 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58

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Torezolid Spectrum

Torezolid(856866-72-3)1HNMR

856866-72-3(Torezolid)Related Search:

bis(((R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl) hydrogen phosphate (R)-3-(3-fluoro-4-(6-(1-methyl-1H-tetrazol-5-yl)pyridin-3-yl) phenyl)-5-(hydroxymethyl)oxazolidin-2-one (S)-(+)-Glycidyl butyrate P,P′-Bis[[(5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl] (diphosphate) (R)-(3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl) phenyl)-2-oxooxazolidin-5-yl)methyl butyrate
Benzyl (4-broMo-3-fluorophenyl)carbaMate Nitazoxanide Tafluprost Rivaroxaban Emtricitabine
Donepezil (5R)-3-(4-BROMO-3-FLUOROPHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE CarbaMic acid, N-[3-fluoro-4-[6-(2-Methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-, phenylMethyl ester 5-BROMO-2-(2-METHYL-2H-TETRAZOL-5-YL)-PYRIDINE 2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
Esomeprazole magnesium Parecoxib Fondaparinux Sodiun
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3- [3-fluoro-4- [6- (2-methyl--2H- tetrazol-5-yl) -3-pyridinyl] phenyl] -5- (hydroxymethyl) -2-oxazolidine ketone Tedizolid free base 3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one TEDIZOLID;TR-700; DA-7157 (R)-3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolid 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidi 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone DA 7157 DA-7157 Torezolid -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one Tedizolid (TR-701) Torezolid (TR-701 (5R)-3-{3-fluoro-4-[6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxyMethyl)-1,3-oxazolidin-2-one Phosphate Specially acetazolaMide (R)-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one (5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-Oxazolidin 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone Torezolid (TR-701 (5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one Tedizolid impurity580 Torezolid USP/EP/BP -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate 2-Oxazolidinone, 3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-, (5R)- DA-7157，Torezolid,TR 700 Torezolid Related substance I Impurity 1.10 Tedizolid (TR 700 Torezolid856866-72-3 (R)-3-(3-fluoro-4-(6-(2-methyl-2H Torezolid-21 (R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one，Torezolid Tedizolid (R)-3-(3-fluoro-4-(6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxyMethyl)oxazolidin-2-one Tedizolidted CS-1826 Tedizolid Impurity 47 Specially thiazole amine Benzenepropanoicacid,6-chloro-β-oxo-,ethylester (R)-3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (Tedizolid Impurity) Terazolamide impurity 23 Tedizolid HCl(free base) (5R)-3-{3-Fluoro-4-[6-(2-Methyl-2H-Tetrazol-5-yl)-Pyridin-3-yl]-Phenyl}-5-Hydroxymethyl-Oxazolidin-2-One (R)-3-(3-fluoro-4-(6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5- (hydroxyMethyl)oxazolidin-2-one, Free base 856866-72-3 856866-44-0 856866-72-7 C17H15FN6O3 Inhibitors Tedizolid intermediates 856866-72-3