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Esomeprazole magnesium
- CAS No.
- 161973-10-0
- Chemical Name:
- Esomeprazole magnesium
- Synonyms
- Chebi:50309;S-Form magnesium salt;Esomeprazole magnesium;(-)-Omeprazole Magnesium;Esomeprazole magnesium API;ESOMEPRAZOLE MAGNESIUM/SODIUM;ESOMEPRAZOLE MAGNESIUM SAMPLE;NEXIUM(esomeprazolemagnesium);EsoMeprazole MagnesiuM(NexiuM);Esomeprazole magnesium USP/EP/BP
- CBNumber:
- CB81104336
- Molecular Formula:
- C34H36MgN6O6S2
- Molecular Weight:
- 713.12
- MOL File:
- 161973-10-0.mol
- Modify Date:
- 2024/6/15 22:11:33
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
Esomeprazole magnesium Chemical Properties,Uses,Production
Uses
Antiulcerative
Definition
ChEBI: A magnesium salt resulting from the formal reaction of magnesium hydroxide with 2 mol eq. of esomeprazole. An inhibitor of gastric acid secretion, it is used for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zolli ger-Ellison syndrome.
General Description
Esomeprazole magnesium,S-bis(5-rnethoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-l-yl) magnesiumtrihydrate (Nexium), is the S-enantiomer ofomeprazole. The benzimidazole PPIs contain a chiral sulfuratom that form an enantiomeric pair that is stable andinsoluble under standard conditions. The S-isomer ofomeprazole has slightly greater PPI activity, and its intrinsicclearance is approximately three times lower thanthat of R-omeprazole (15 vs. 43μL/min). The lowerclearance of S-omeprazole is related to slower metabolicclearance by the CYP2C19 isozyme. Although Romeprazoleis primarily transformed to the 5-hydroxymetabolite, the S-isomer is metabolized by O-demethylationand sulfoxidation, which contribute little to intrinsicclearance.
Esomeprazole magnesium Preparation Products And Raw materials
Global( 274)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Macleods Pharmaceuticals Limited | +91-2266762800 +91-2266762800 | Maharashtra, India | 116 | 58 | Inquiry |
| KRS Pharmaceuticals Pvt. Ltd. | +91-4023176686 +91-9848996298 | Hyderabad, India | 36 | 58 | Inquiry |
| Nosch Labs Pvt Ltd | +91-4048557474 +91-9948222287 | Hyderabad, India | 58 | 58 | Inquiry |
| Prachin Chemicals Saykha Private Limited | +91-9537763493 +91-9904988839 | Gujarat, India | 16 | 58 | Inquiry |
| A.B.ENTERPRISES | +91-9223381464 +91-9223381464 | Maharashtra, India | 78 | 58 | Inquiry |
| Alfa Omega Pharma | +91-8050045945 +91-9972665399 | Maharashtra, India | 126 | 58 | Inquiry |
| Globela Industry Pvt Ltd | +91-2616158000 +91-9998199919 | Gujarat, India | 98 | 58 | Inquiry |
| Sibram Pharmaceutical | +91-8655777550 +91-8655777550 | Maharashtra, India | 244 | 58 | Inquiry |
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161973-10-0(Esomeprazole magnesium)Related Search:
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ESOMEPRAZOLE MAGNESIUM TRIHYDRATE,ESOMEPRAZOLE MAGNESIUM TRIHYDRATE USP
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MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, (T-4)-
ESOMEPRAZOLE MAGNESIUM/SODIUM
(T-4)-bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-magnesium
5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt
ESOMEPRAZOLE MAGNESIUM SAMPLE
Esomeprazole magnesium
Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium
Chebi:50309
EsoMeprazole MagnesiuM(NexiuM)
EsMeprazole Magne-siuM Trihydrate
S-Form magnesium salt
Esomeprazole magnesium Esomeprazole magnesium(API)
Esomeprazole magnesium 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole magnesium salt
Esomeprazole Magnesium(Random Configuration)
NEXIUM(esomeprazolemagnesium)
Magnesium Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]benzimidazol-1-ide]
(-)-Omeprazole Magnesium
Esomeprazole magnesium USP/EP/BP
Esomeprazole magnesium (S-Omeprazole magnesium)
Esomeprazole magnesiumQ: What is
Esomeprazole magnesium Q: What is the CAS Number of
Esomeprazole magnesium Q: What is the storage condition of
Esomeprazole magnesium Q: What are the applications of
Esomeprazole magnesium
Esomeprazole magnesium API
(S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, magnesium salt (2:1)
magnesium(2+) 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazol-1-ide 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazol-1-ide
161973-10-0
161973-10-3
2C17H18N3O3S2Mg
C17H18N3O3S2Mg
Inhibitors
Esomeprazole