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ChemicalBook > Product Catalog >API >Digestive system drugs >Antacid and Mucosal protective Drugs >Esomeprazole sodium

Esomeprazole sodium

Esomeprazole sodium Structure
CAS No.
161796-78-7
Chemical Name:
Esomeprazole sodium
Synonyms
Esomeprazole Na;Nexium sodium;EsoMeprazole sod;ESOMEPRAZOLE SODIUM;Esomeprazoleandsalts;(S)-OMeprazole sodiuM;Esomeprazole Sodium D3;Esomeprazole sodium CRS;ESOMEPRAZOLE NA (34-37%);Esomeprazole impurity API
CBNumber:
CB7123722
Molecular Formula:
C34H36MgN6O6S2
Molecular Weight:
713.12
MOL File:
161796-78-7.mol
MSDS File:
SDS
Modify Date:
2024/7/30 16:49:16
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Esomeprazole sodium Properties

Melting point 156 °C (approx)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)
form Solid
color Pale Beige to Brown
Stability Hygroscopic
InChI InChI=1S/C17H18N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3;/q-1;+1
InChIKey RYXPMWYHEBGTRV-UHFFFAOYSA-N
SMILES C1(S(=O)CC2=NC=C(C)C(OC)=C2C)N([Na])C2=C(C=C(C=C2)OC)N=1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H314-H361-H412
Precautionary statements  P501-P273-P260-P270-P202-P201-P264-P280-P308+P313-P303+P361+P353-P301+P330+P331-P363-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405

Esomeprazole sodium Chemical Properties,Uses,Production

Chemical Properties

Beige Solid

Uses

Esomeprazole sodium is a commonly used anti-ulcer drug. It was successfully developed by AstraZeneca for the first time. It is a proton pump inhibitor. The drug of choice for related diseases.
(S)-Omeprazole is the (S)-enantiomer of Omeprazole (O635000) a gastric proton-pump inhibitor. (S)-Omeprazole is more potent that its (R)-enantiomer and is used in the treatment of gastroesophageal ref lux disease as well as gastrointestinal ulcers associated with Crohn's disease.

brand name

Nexium (AstraZeneca).

Mode of action

Esomeprazole Sodium is the sodium salt of the S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell.

Esomeprazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Esomeprazole sodium Suppliers

Global( 498)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Jigs Chemical ltd +919099003427 Gujarat, India 239 58 Inquiry
Micro Orgo Chem +91-91-022-24969510 +91-9082984052 Mumbai, India 66 58 Inquiry
Vivimed Labs Ltd +914066086608 Telangana, India 61 58 Inquiry
Lee Pharma Ltd +91-9849085929 +91-9849085929 Hyderabad, India 42 58 Inquiry
Macleods Pharmaceuticals Limited +91-2266762800 +91-2266762800 Maharashtra, India 116 58 Inquiry
Hetero Drugs Limited +91-4023704923 +91-4023704923 Telangana, India 296 58 Inquiry
Prachi Pharmaceuticals Pvt Ltd +919004877711 Mumbai, India 36 58 Inquiry
Integrin Life Sciences. Pvt. Ltd. +91-4040265469 +91-9849990870 Hyderabad, India 90 58 Inquiry
Everest Organics Limited +91-4040028838 +91-9440409996 Hyderabad, India 61 58 Inquiry
KRS Pharmaceuticals Pvt. Ltd. +91-4023176686 +91-9848996298 Hyderabad, India 36 58 Inquiry
Supplier Advantage
Jigs Chemical ltd 58
Micro Orgo Chem 58
Vivimed Labs Ltd 58
Lee Pharma Ltd 58
Macleods Pharmaceuticals Limited 58
Hetero Drugs Limited 58
Prachi Pharmaceuticals Pvt Ltd 58
Integrin Life Sciences. Pvt. Ltd. 58
Everest Organics Limited 58
KRS Pharmaceuticals Pvt. Ltd. 58

Esomeprazole sodium Spectrum

Esomeprazole sodium(161796-78-7)1HNMR

161796-78-7(Esomeprazole sodium)Related Search:

Esomeprazole magnesium Sodium sulfate Omeprazole sodium sterile ETHANE Dimethyl sulfate
Dimethyl fumarate Dacthal Anisole Dimethyl ether N,N-Dimethylformamide
Sodium hydroxide Sodium chlorite Sodium chloride Benzimidazole Sodium acetate
(Trifluoromethoxy)benzene OMEPRAZOLE MAGNESIUM Cefazolin sodium salt
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(S)-OMeprazole sodiuM 1H-BENZIMIDAZOLE, 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-, SODIUM SALT ESOMEPRAZOLE SODIUM Esomeprazoleandsalts 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt SodiuM (S)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide odiuM (R)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide EsoMeprazole sod Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-i (S)-Omeprazole Sodium Salt 1H-BenziMidazole,6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-, sodiuMsalt (1:1) Esomeprazole sodium 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt Esomeprazole sodium impurity Calcium Folinate Leucovorin Calcium 5-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol- 5-METHOXY-2-((S)-((4-METHOXY-3,5-DIMETHY L-2-PYRIDIYL)METHYL)SULFINL)-1H-BENZIMID AZOLE-1-YL)SODIUM 5-methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-3-ide 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methane]sulfinyl}-1-sodio-1H-1,3-benzodiazole sodium (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide sodium (R)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide Esomeprazole sodium CRS sodium 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methane]sulfinyl}-1H-1,3-benzodiazol-1-ide Nexium sodium Esomeprazole sodium USP/EP/BP 6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt Esomeprazole sodium (S-Omeprazole sodium) Esomeprazole Impurities523 Esomeprazole Impurities522 Esomeprazole sodiumQ: What is Esomeprazole sodium Q: What is the CAS Number of Esomeprazole sodium Q: What is the storage condition of Esomeprazole sodium Q: What are the applications of Esomeprazole sodium Esomeprazole sodium (Y0002075) Esomeprazole Sodium D3 USDMF & CEP grade Esomeprazole Sodium Esomeprazole Na Esomeprazole sodium (Nexium) Esomeprazole impurity API ESOMEPRAZOLE NA (34-37%) 161796-78-7 C17H20N3NaO3S C17H18N3O3NaS 3674 Inhibitors zjh ACTIVE PHARMACEUTICAL INGREDIENTS API bc0001 161796-78-7