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Esomeprazole magnesium trihydrate

Esomeprazole magnesium trihydrate Structure
CAS No.
217087-09-7
Chemical Name:
Esomeprazole magnesium trihydrate
Synonyms
Nexium;EsomepazoleTrihydrate;Esomeprazole Mg Trihydrate;ESOPMEPRAZOLE MG TRIHYDRATE;EsoMeprazole Meg. Trihydrate;Omeprazole 8.5%/12.5% pellels;Esomeprazole Magnesium (10 mg);Esomeprazole Magnesium (25 mg);Omeprazole Magnesium Trihydrate;EsoMeprazole Magnesiu Trihydrate
CBNumber:
CB9740619
Molecular Formula:
C34H38MgN6O7S2
Molecular Weight:
731.14
MOL File:
217087-09-7.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43

Esomeprazole magnesium trihydrate Properties

Melting point 184-189°C (dec.)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility Slightly soluble in water, soluble in methanol, practically insoluble in heptane.
form Solid
color White to off-white
InChI InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;
InChIKey VEVZQDGATGBLIC-UHFFFAOYSA-N
SMILES C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O
CAS DataBase Reference 217087-09-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
HS Code  2933399090

Esomeprazole magnesium trihydrate price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1585 Esomeprazole Magnesium Pharmaceutical Secondary Standard; Certified Reference Material 217087-09-7 1G ₹16540.6 2022-06-14 Buy
Product number Packaging Price Buy
PHR1585 1G ₹16540.6 Buy

Esomeprazole magnesium trihydrate Chemical Properties,Uses,Production

Chemical Properties

Off-White Powder

Uses

esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.

  1. Zollinger-Ellison syndrome
  2. Peptic ulcer, site unspecified
  3. Duodenal ulcer
  4. Gastric ulcer
  5. Gastro-oesophageal reflux disease
Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
  1. Gastro-Oesophageal Reflux Disease (GORD):
  2. treatment of erosive reflux oesophagitis;
  3. long-term management of patients with healed oesophagitis to prevent relapse;
  4. symptomatic treatment of gastro-oesophageal reflux disease (GORD).
In combination with appropriate antibiotics for:
  1. healing of duodenal ulcer associated with Helicobacter pylori;
  2. eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
  3. Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
  4. Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
  5. Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.

brand name

Nexium (AstraZeneca).

Biological Activity

Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent, orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release by inhibiting V-H+-ATPases.

Esomeprazole magnesium trihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 416)Suppliers
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Esomeprazole magnesium trihydrate Spectrum

ESOMEPRAZOLE MAGNESIUM TRIHYDRATE bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate (T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium Nexium ESOPMEPRAZOLE MG TRIHYDRATE 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-1-ide 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide EsoMeprazole Meg. Trihydrate Esomeprazole Magnesium (10 mg) ESOMEPRAZOLE MAGNESIUM TRIHYDRATE USP (S)-OMeprazole MagnesiuM trihydrate MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, hydrate (1:3), (T-4)- Esomeprazole magnesium trihydrate Bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzylimidazole-1-yl) magnesium trihydrate Esomeprazole Magnesium (25 mg) EsoMeprazole Magnesiu Trihydrate Esomeprazole magnesium thihydrate Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, hydrate (1:3), (T-4)- Esomeprazole Magnesium Dihydrate/Trihydrate Magnesium,bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, hydrate Esomeprazole agnesium trihydrate Omeprazole Magnesium Trihydrate Esomeprazole magnesium trihydrate CRS Nesomeprazole magnesium trihydrate EsomepazoleTrihydrate Esomeprazole Magnesium (1249789) Omeprazole(Esomeprazole Magnesium) Trihydrate Esomeprazole Magnesium Tri-Hydrate IP/Ph. Eur./BP Omeprazole 8.5%/12.5% pellels Esomeprzole magnesium Trihydrate Esomperazole Magnessium Trihydrate Esomeprazole Mg Trihydrate 217087-09-7 2C17H18N3O3SMg3H2O C34H36MgN6O6S23H2O C34H42MgN6O9S2 71312 Acid pump inhibitors Chiral Reagents Inhibitors Intermediates & Fine Chemicals Pharmaceuticals