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Salbutamol

Salbutamol Structure
CAS No.
34391-04-3
Chemical Name:
Salbutamol
Synonyms
Salbutamol;r-albuterol;LEVALBUTEROL;Levalbutreol;(L)-ALBUTEROL;Levosalbutamol;R-SALBUTAMOL HCL;LEVALBUTEROL HCL;LEVOSALBUTEROLHCL;Levosalbutamol (Levalbuterol)
CBNumber:
CB0275903
Molecular Formula:
C13H21NO3
Molecular Weight:
239.31
MOL File:
34391-04-3.mol
Modify Date:
2024/5/11 20:10:50
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Salbutamol Properties

Boiling point 433.5±40.0 °C(Predicted)
Density 1.152±0.06 g/cm3(Predicted)
pka 9.99±0.31(Predicted)
InChI InChI=1/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3/t12-/s3
InChIKey NDAUXUAQIAJITI-PLAQIDKDNA-N
SMILES C1(=CC=C(O)C(CO)=C1)[C@@H](O)CNC(C)(C)C |&1:9,r|
CAS DataBase Reference 34391-04-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  22
Safety Statements  36

Salbutamol Chemical Properties,Uses,Production

Description

Levalbuterol was launched in the US for the treatment or prevention of bronchospasm in patients with reversible obstructive airway disease. It is the single R-enantiomer version of racemic albuterol (salbutamol) marketed for more than 30 years as a mainstay in the treatment of asthma. The R-isomer can be obtained with an excellent optical purity by enantiomeric purification based on the separation of diastereomeric tartrates. This isomer retains solely the desired bronchodilating effect of the racemic mixture due to a potent agonistic effect on β2-adrenoceptors, with a lower incidence of β- mediated side effects such as pulse rate increase, tremor and decrease in blood glucose and potassium levels. A pivotal clinical trial with two doses of levalbuterol and racemic albuterol, given by nebulization, demonstrated a greater improvement in lung function for the pure enantiomer levalbuterol.

Uses

(R)-Salbutamol is used in composition and methods to reduce beta-agonist-mediated tachyphylaxis.

Salbutamol Preparation Products And Raw materials

Raw materials

METHYL 5-ACETYLSALICYLATE Borane-methyl sulfide complex Palladium hydroxide tert-Butylamine Hydrogen bromide

Preparation Products

Salbutamol Suppliers

Global( 73)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
J S LABS +91-7330612784 +91-7330612784 Tamil Nadu, India 160 58 Inquiry
Venkatasai Life Sciences +91-9908134868 +91-8008303069 Hyderabad, India 186 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Medilink Pharmachem +91 (79) 3007-0133 New Delhi, India 424 50 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Sigma Audley +86-18336680971 +86-18126314766 China 497 58 Inquiry
hebei hongtan Biotechnology Co., Ltd +86-86-1913198-3935 +8617331935328 China 973 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
Supplier Advantage
J S LABS 58
Venkatasai Life Sciences 58
Ralington Pharma 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Medilink Pharmachem 50
CLEARSYNTH LABS LTD. 58
Sigma Audley 58
hebei hongtan Biotechnology Co., Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
career henan chemical co 58

34391-04-3(Salbutamol)Related Search:

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dl-salbutamo LEVALBUTEROL HCL (SALBUTAMOL HCL) 1,3-Benzenedimethanol
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LEVALBUTEROL LEVALBUTEROL HCL (L)-ALBUTEROL R-SALBUTAMOL HCL (-)-alpha(sup1)-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-1,3-benzenedime 1,3-benzenedimethanol,alpha(sup1)-(((1,1-dimethylethyl)amino)methyl)-4-hydrox alpha’-diol,alpha(sup1)-((tert-butylamino)methyl)-4-hydroxy-m-xylene-alph r-albuterol 2-(hydroxymethyl)-4-[1-hydroxy-2-(tert-butylamino)ethyl]phenol LEVOSALBUTEROLHCL 1,3-Benzenedimethanol, a1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (a1R)- (9CI) 1,3-Benzenedimethanol, a1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (R)- Levosalbutamol m-Xylene-a,a'-diol, a1-[(tert-butylamino)methyl]-4-hydroxy-, (R)-(-)- (8CI) 2-(hydroxymethyl)-4-[(1R)-1-hydroxy-2-(tert-butylamino)ethyl]phenol 4-[2-(tert-Butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol Levalbutreol Salbutamol (R)-1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(1,1-dimethylethylamino)ethanol (R)-1-(4-Hydroxy-3-hydroxymethylphenyl)-2-tert-butylaminoethanol (R)-4-Hydroxy-3-(hydroxymethyl)-α-[[(tert-butyl)amino]methyl]benzyl alcohol (αR)-α-[(tert-Butylamino)methyl]-4-hydroxy-1,3-benzenedimethanol 4-[(1R)-2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)phenol 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol 4-[(1R)-2-(tert-butylamino)-1-hydroxy-ethyl]-2-methylol-phenol Levosalbutamol (Levalbuterol) 2-(Hydroxymethyl)-4-{(1R)-1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}phenol 1,3-Benzenedimethanol, α1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, (α1R)- (+/-) - Albuterol (Levalbuterol) 34391-04-3 51022-72-9 C13H21NO3 API