3-METHYL-1H-INDAZOLE
- CAS No.
- 3176-62-3
- Chemical Name:
- 3-METHYL-1H-INDAZOLE
- Synonyms
- 3-METHYL-1H-INDAZOLE;1H-Indazole, 3-methyl-;Benzenamine,N,N,3,9-tetramethyl-;1-Propanone,1-(3,9-dichlorophenyl)-
- CBNumber:
- CB0303785
- Molecular Formula:
- C8H8N2
- Molecular Weight:
- 132.16
- MOL File:
- 3176-62-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/8 20:25:11
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H317-H319-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HS Code | 2933998090 |
3-METHYL-1H-INDAZOLE Chemical Properties,Uses,Production
Description
3-Methyl-1H-indazole is a heterocyclic alkyl compound containing nitrogen and three methyl groups. It is used as an intermediate in the synthesis of other compounds. It has been shown to have anti-inflammatory properties in vitro. It also inhibits neutrophil chemotaxis and may be used to treat inflammatory diseases such as trigeminal neuralgia or heart disease. 3-Methyl-1H-indazole has also been shown to inhibit histamine H3 receptor activity, which may account for its effects on eye diseases and bladder cancer.
Uses
3-Methyl-1H-indazole is an intermediate compound. It can be used as an organic synthesis reagent for the preparation of 3-methyl-1H-indazol-5-amine and 3-methyl-5-nitro-1H-indazole compounds. In addition, the 3-Methyl-1H-indazole derivatives (1a-1d and 2a-2d) have antimicrobial effects, both having antibacterial activity against Bacillus subtilis and Escherichia coli[1].
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 25, p. 1817, 1988 DOI: 10.1002/jhet.5570250641
Synthesis, p. 982, 1984
References
[1] FARRUKH SHAIKH. Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives[J]. Intelligent Pharmacy, 2024. DOI:10.1016/j.ipha.2023.09.003.
3-METHYL-1H-INDAZOLE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Indus Biosciences Pvt. Ltd. | +91 (40) 2717-1045 | New Delhi, India | 43 | 50 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ROSEWA HOLDING GROUP CO.,LIMITED | +86-023-62871537 | China | 2851 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | China | 2121 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | CHINA | 21149 | 58 | Inquiry |