Granisetron Hydrochloride
![Granisetron Hydrochloride Structure](CAS/GIF/107007-99-8.gif)
- CAS No.
- 107007-99-8
- Chemical Name:
- Granisetron Hydrochloride
- Synonyms
- GRANISETRON HYDROCHLORIDE;GRANISETRON HCL;KYTRIL;1-Methyl-N-[(1β,3α,5β)-9-methyl-9-azabicyclo[3.3.1]nonane-3-yl]-1H-indazole-3-carboxamide·hydrochloride;Kitryl;BRL-43694A;Gransetron HCl;GranisetronBase;midehydrochloride;GranisetronHclFda
- CBNumber:
- CB9728851
- Molecular Formula:
- C18H25ClN4O
- Molecular Weight:
- 348.87
- MOL File:
- 107007-99-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
Melting point | 290-292°C |
---|---|
storage temp. | Room temp |
solubility | H2O: >10mg/mL |
form | solid |
color | white to off-white |
Merck | 14,4536 |
CAS DataBase Reference | 107007-99-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-62-37/38-36/37/38-36 | |||||||||
Safety Statements | 26-36-37-24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | NK7882200 | |||||||||
HS Code | 29399990 | |||||||||
NFPA 704 |
|
Granisetron Hydrochloride price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1616 | Granisetron Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 107007-99-8 | 500MG | ₹12535.35 | 2022-06-14 | Buy |
TCI Chemicals (India) | G0401 | Granisetron Hydrochloride | 107007-99-8 | 200MG | ₹3200 | 2022-05-26 | Buy |
TCI Chemicals (India) | G0401 | Granisetron Hydrochloride | 107007-99-8 | 1G | ₹9700 | 2022-05-26 | Buy |
Granisetron Hydrochloride Chemical Properties,Uses,Production
Description
Granisetron hydrochloride is the second selective 5HT-3-antagonist approved for the management of nausea and vomiting induced by cancer chemotherapy.Like ondansetron, granisetron hydrochloride is superior to metoclopramide in both efficacy and side effect profile. The compound appears to be effective both as a prophylactic agent and in blocking vomiting once started.
Chemical Properties
White to Off-White Crystalline Sold
Uses
A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemothera py. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarini c receptor
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biological Activity
5-HT 3 receptor antagonist that possesses potent antiemetic activity.
Granisetron Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
NILKANTH HEALTH CHEM (I) PRIVATE LIMITED | +91 8000452862 | Gujarat, India | 17 | 58 | Inquiry |
SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
WARUKSHA LABORATORIES PVT LTD | +91-7485988764 +91-7485988764 | Gujarat, India | 77 | 58 | Inquiry |
Nivika Chemo Pharma Pvt Ltd | +91-9824176501 +91-9824176501 | Gujarat, India | 15 | 58 | Inquiry |
Cipla Ltd | +912224826000 | Maharashtra, India | 133 | 58 | Inquiry |
Chemino Pharma Ltd | +91-8689897373 +91-8689897373 | Maharashtra, India | 31 | 58 | Inquiry |
Orchid Pharma Ltd. (Formerly Known as Orchid Chemicals and Pharmaceuticals Ltd.) | +91-4428244254 +91-4428244254 | Tamil Nadu, India | 28 | 58 | Inquiry |
Raising Sun Pharma | +91-9399941155 +91-9399941155 | Telangana, India | 127 | 58 | Inquiry |
Swati Spentose Pvt Ltd | +91-2261505232 +91-2261505232 | Maharashtra, India | 44 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
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