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ALOSETRON

CAS No.: 122852-42-0

Chemical Name:: ALOSETRON

Synonyms: ALOSETRON;aloosetron.;GR-68755X;GR-68755;ALOSETRON USP/EP/BP;Alosetron (GR-68755X;GR 68755; GR 68755X; LOTRONEX;GR-68755;GR68755;9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)- 1,2,3,9-Tetrahydro-;5-METHYL-2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]-3,4-DIHYDROPYRIDO[4,3-B]INDOL-1-ONE;9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)-1,2,3,9-Tetrahydro-Carbazol-4-One Hydrochloride;5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one

CBNumber:: CB8149787

Molecular Formula:: C17H18N4O

Molecular Weight:: 294.35

MOL File:: 122852-42-0.mol

Modify Date:: 2023/5/21 10:59:17

Request For Quotation

ALOSETRON Properties

Melting point	238-240 °C
Boiling point	648.1±55.0 °C(Predicted)
Density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO
form	Powder
pka	14.10±0.10(Predicted)

SAFETY

Risk and Safety Statements

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36

ALOSETRON Chemical Properties,Uses,Production

Chemical Properties

crystalline powder

Uses

Anti-emetic.

Indications

Alosetron (Lotronex) is a 5-HT3 receptor antagonist. Blocking this receptor results in decreased GI motility. Alosetron received FDA approval in February 2000 for the treatment of women with diarrhea-predominant IBS. In November 2000, at the request of the FDA, the drug was voluntarily withdrawn due to reported cases of ischemic colitis, including some fatalities.

Definition

ChEBI: A pyrido[4,3-b]indole compound having a 5-methyl-1H-imidazol-4-ylmethyl group at the 2-position.

ALOSETRON Preparation Products And Raw materials

Raw materials

1-TRITYL-1H-IMIDAZOLE-4-METHANOL Sodium hydride Polyphosphoric acid Thionyl chloride Maleic acid

Hydroxylamine hydrochloride 2-Methoxyethanol

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Preparation Products

ALOSETRON Suppliers

Global( 86)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6754	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6739	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29810	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32161	58	Inquiry
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	China	2251	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	China	7724	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9311	58	Inquiry
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	China	988	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	China	25356	58	Inquiry

Supplier	Advantage
Ralington Pharma	58
Pharma Affiliates	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Xi'an MC Biotech, Co., Ltd.	58
Shaanxi Dideu Medichem Co. Ltd	58
Baoji Guokang Bio-Technology Co., Ltd.	58
Sinoway Industrial co., ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

122852-42-0(ALOSETRON)Related Search:

Phenylbutazone IMIPRAMINE Cytarabine Chlorpromazine ONDANSETRON FOR LC SYSTEM SUITABILITY

Thalidomide ALOSETRON Lurosetron ALOSETRON HCL,ALOSETRON HYDROCHLORIDE 2,3,4,5-Tetrahydro-5-methyl-1H-pyrido[4,3-b]indol-1-one

2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indole 3-CARBAMOYL-2-METHYLINDOLE Alosetron-d3 Hydrochloride (1-Methyl-1H-indol-3-yl)-methylamine 1H-Indole-3-carboxamide(9CI)

1-METHYL-4,5,6,7-TETRAHYDRO-1H-PYRROLO[3,2-C]PYRIDINE 2-METHYL-3-N,N-DIMETHYLAMINOMETHYLINDOLE N-(2-(1-METHYL-1H-PYRROL-2-YL)ETHYL)FORMAMIDE

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ALOSETRON ALOSETRON 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one 5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one 5-METHYL-2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]-3,4-DIHYDROPYRIDO[4,3-B]INDOL-1-ONE GR-68755X;GR-68755 Alosetron (GR-68755X GR 68755; GR 68755X; LOTRONEX;GR-68755;GR68755 1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]- ALOSETRON USP/EP/BP 9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)- 1,2,3,9-Tetrahydro- 9-methyl-3-(5-methyl-3H-Imidazol-4-ylmethyl)-1,2,3,9-Tetrahydro-Carbazol-4-One Hydrochloride aloosetron. 122852-42-0