ChemicalBook > Product Catalog >API >Antineoplastic agents >Other antineoplastic Drugs >Lonidamine

Lonidamine

CAS No.: 50264-69-2

Chemical Name:: Lonidamine

Synonyms: dica;lonidamin;af1890;LONIDAMINE;doridamina;Lonidnmine;LONIDAMING;AF-1890：DICA;Lonidamine, >=99%;DICLONDAZOLIC ACID

CBNumber:: CB6493965

Molecular Formula:: C15H10Cl2N2O2

Molecular Weight:: 321.16

MOL File:: 50264-69-2.mol

MSDS File:: SDS

Modify Date:: 2024/7/26 15:15:06

Request For Quotation

Lonidamine Properties

Melting point	207-209°C
Boiling point	537.9±45.0 °C(Predicted)
Density	1.4835 (rough estimate)
refractive index	1.6070 (estimate)
storage temp.	Sealed in dry,2-8°C
solubility	Soluble in DMSO (up to 25 mg/ml).
form	solid
pka	3.00±0.10(Predicted)
color	White
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey	WDRYRZXSPDWGEB-UHFFFAOYSA-N
CAS DataBase Reference	50264-69-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H302-H351-H360

Precautionary statements

P201-P301+P312+P330-P308+P313

Hazard Codes

Risk Statements

60-22-40

Safety Statements

53-22-36/37/39-45

WGK Germany

RTECS

NK7886000

HS Code

29339900

Toxicity

LD50 in mice, rats (mg/kg): 900, 1700 orally; 435, 525 i.p. (Heywood)

NFPA 704

	0
2		0

Lonidamine price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	L4900	Lonidamine mitochondrial hexokinase inhibitor	50264-69-2	5MG	₹11409.55	2022-06-14	Buy
Sigma-Aldrich(India)	L4900	Lonidamine mitochondrial hexokinase inhibitor	50264-69-2	25MG	₹50217.18	2022-06-14	Buy
ottokemi	L 3912	Lonidamine	50264-69-2	5mg	₹39069	2022-05-26	Buy
ottokemi	L 3912	Lonidamine	50264-69-2	25mg	₹139059	2022-05-26	Buy

Product number	Packaging	Price	Buy
L4900	5MG	₹11409.55	Buy
L4900	25MG	₹50217.18	Buy
L 3912	5mg	₹39069	Buy
L 3912	25mg	₹139059	Buy

Lonidamine Chemical Properties,Uses,Production

Description

Lonidamine is an antineoplastic agent reportedly effective for the treatment of various cancers, including lung, breast, prostate and brain tumors. Its clinical effect appears to be associated with changes in cellular energy metabolism.

Uses

contraceptive, spermicidal

Definition

ChEBI: A member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively.

Biological Activity

Anticancer and antispermatogenic agent in vitro and in vivo . Inhibits cellular energy metabolism in some cells via inhibition of mitochondrial hexokinase. Also blocks CFTR Cl - channels in vitro .

Lonidamine Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate Isatin Potassium iodide Sodium nitrite 7-Hydroxygranisetron

2,4-Dichlorobenzoyl chloride 2’-Bromo-2-hydroxyacetophenone 3-(HYDROXYMETHYL)INDAZOLE Methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate 1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER

2'-Bromoacetophenone 2,4-Dichlorobenzyl chloride

chevron_left

1of3

chevron_right

Preparation Products

Lonidamine Suppliers

Global( 246)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
OCEAN TRADING CORPORATION	+91(22) 24921669	New Delhi, India	6211	58	Inquiry
Otto Chemie Pvt. Ltd.	+91 9820041841	Mumbai, India	5873	58	Inquiry
Hebei Guanlang Biotechnology Co,.LTD	+86-19930503253; +8619930503252	China	5835	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29897	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	13102	58	Inquiry
SIMAGCHEM CORP	+86-13806087780	China	17367	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
OCEAN TRADING CORPORATION	58
Otto Chemie Pvt. Ltd.	58
Hebei Guanlang Biotechnology Co,.LTD	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58

50264-69-2(Lonidamine)Related Search:

Indazole-3-carboxylic acid Triphenylphosphine Dichloroethane Thionyl chloride Citric acid

Folic acid Hyaluronic acid 2-Phenylphenol Quinclorac Sodium dichloroisocyanurate

Ethyl 2-(Chlorosulfonyl)acetate Dichlorodiphenylsilane Voriconazole Ascoric Acid Phenylacetone

1-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 3-METHYL-1H-INDAZOLE 1H-INDAZOLE-3-CARBALDEHYDE

chevron_left

1of4

chevron_right

af1890 1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid 1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]- 1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid 1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci Lonidamine, >=99% 1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid DICLONDAZOLIC ACID LONIDAMINE 1-[2,4-DICHLOROBENZYL]-1H-INDAZOLE-3-CARBOXYLIC ACID 1-[(2,4-DICHLOROPHENYL)METHYL]-1H-INDAZOLE-3-CARBOXYLIC ACID doridamina 1-(2,4-Dichlorobenzyl)indazole-3-carboxylic acid Lonidnmine 1-[（2,4-Dichlorophenyl）methyl]-1H-indazole-3-carboxylic acid, DICA 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid, Diclondazolic acid 13iclondazolic Acid AF-1890：DICA 1-((2,4-dichlorophenyl)methyl)-1h-indazole-3-carboxylicaci 1-[(2，4-Dichloropheny1) methyl]-1H-indazole-3-carboxylic acid LONIDAMING Lonidamine USP/EP/BP Lonidamine (AF1890) Lonidamine, 99%, mitochondrial hexokinase inhibitor lonidamin dica 50264-69-2 C15H10Cl2N2O2 Biochemicals and Reagents BioChemical Hexokinase (mitochondrial), cellular respiration, and glycolysis D to K Enzyme Inhibitors Enzyme Inhibitors by Enzyme Enzymes, Inhibitors, and Substrates API DORIDAMINA inhibitor Anti-cancer&immunity