Isatin
- CAS No.
- 91-56-5
- Chemical Name:
- Isatin
- Synonyms
- 1H-Indole-2,3-dione;satin;Isatine;Isotin;lsatin;ISATIC ANHYDRIDE;2,3-INDOLINEDIONE;2,3-DIKETOINDOLINE;ISATIN;IsatinGr
- CBNumber:
- CB2447182
- Molecular Formula:
- C8H5NO2
- Molecular Weight:
- 147.13
- MOL File:
- 91-56-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/6 16:32:36
| Melting point | 193-195 °C (dec.) (lit.) |
|---|---|
| Boiling point | 267.22°C (rough estimate) |
| Density | 1.3067 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.4700 (estimate) |
| Flash point | 220 °C |
| storage temp. | Store below +30°C. |
| solubility | soluble |
| form | Powder |
| pka | 10.34±0.20(Predicted) |
| color | Orange |
| PH | 7 (1.9g/l, H2O, 20℃) |
| Water Solubility | Soluble in water (1.9 g/L at 20°C). |
| Decomposition | 194 ºC |
| Merck | 14,5104 |
| BRN | 383659 |
| Stability | Stable. Incompatible with strong acids. |
| InChIKey | JXDYKVIHCLTXOP-UHFFFAOYSA-N |
| LogP | 0.45 |
| CAS DataBase Reference | 91-56-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Isatin(91-56-5) |
| EPA Substance Registry System | 1H-Indole-2,3-dione (91-56-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | NL7873000 | |||||||||
| Autoignition Temperature | 220 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29337900 | |||||||||
| NFPA 704 |
|
Isatin price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 114618 | Isatin 97% | 91-56-5 | 5G | ₹2460 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 114618 | Isatin 97% | 91-56-5 | 100G | ₹2950 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 114618 | Isatin 97% | 91-56-5 | 500G | ₹9807.45 | 2022-06-14 | Buy |
| TCI Chemicals (India) | I0080 | Isatin min. 98.0 % | 91-56-5 | 25G | ₹2300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | I0080 | Isatin min. 98.0 % | 91-56-5 | 100G | ₹5200 | 2022-05-26 | Buy |
Isatin Chemical Properties,Uses,Production
Chemical Properties
orange-red powder or crystals
Uses
Isatin is an endogenous monoamine oxidize (MAO) inhibitor involved in stress and anxiety. Additionally, isatin inhibits alkaline phosphatase (ALP), nitric oxide (NO)-stimulated soluble guanylate cyclase, and other enzymes. Isatins undergo a one-pot Wolff-Kishner like reduction with hydrazine hydrate, under surprisingly mild conditions, to give the corresponding oxindoles. It is used as chromatographic spray reagent for amino acid detection.
Definition
ChEBI: An indoledione that is the 2,3-diketo derivative of indole.
Purification Methods
Crystallise isatin from amyl alcohol and sublime it at 180o/1mm. In aqueous NaOH the ring opens to yield sodium o-aminobenzoylformate. [Beilstein 21 II 327, 567, 21 III/IV 4981, 21/10 V 221.]
Isatin Preparation Products And Raw materials
Raw materials
Preparation Products
5-IODOISATIN
1-(2,6-Dichlorophenyl)indole-2,3-dione
Solvent Yellow 114
1-Methylindazole-3-carboxylic acid
6-BROMO-2-METHYL-QUINOLINE-4-CARBOXYLIC ACID
3-(HYDROXYMETHYL)INDAZOLE
Lonidamine
1-Acetyl-1H-indole-2,3-dione
1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE
7-Hydroxygranisetron
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Global( 522)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Bhakti Impex | +919822268653 | Pune, India | 76 | 58 | Inquiry |
| GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED | +91-91-22-25278801 +91-2225278801 | Mumbai, India | 83 | 58 | Inquiry |
| ssk bioscience pvt. ltd | +91-8106421818 +91-8106421818 | Hyderabad, India | 40 | 58 | Inquiry |
| JIVICHEM SYNTHESIS PVT LTD | +91-7028392790 +91-7028392790 | Maharashtra, India | 337 | 58 | Inquiry |
| Otto Chemie Pvt Ltd | +91-2222070099 +91-2266382599 | Maharashtra, India | 429 | 58 | Inquiry |
| Shubham Specialty Products Pvt Ltd | +91-2249733812 +91-9867728601 | Mumbai, India | 38 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Supplier | Advantage |
|---|---|
| Bhakti Impex | 58 |
| GRINDLAYS PHARMACEUTICALS PRIVATE LIMITED | 58 |
| ssk bioscience pvt. ltd | 58 |
| JIVICHEM SYNTHESIS PVT LTD | 58 |
| Otto Chemie Pvt Ltd | 58 |
| Shubham Specialty Products Pvt Ltd | 58 |
| JSK Chemicals | 58 |
| ALPHA CHEMIKA | 43 |
| Scientific OEM | 38 |
| CHEMSWORTH | 30 |
Related articles
- Synthesis of Isatin
- Isatin was first of all reported by Erdman and Laurent in 1841 as a new product from the oxidation of indigo by nitric and chr....
- Jan 24，2022
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