Lonidamine
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- ₹11409.55 - ₹139059
- Product name: Lonidamine
- CAS: 50264-69-2
- MF: C15H10Cl2N2O2
- MW: 321.16
- EINECS:256-510-0
- MDL Number:MFCD00866285
- Synonyms:af1890 ;1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid;1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]-;1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid ;1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci ;Lonidamine, >=99%;1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid;DICLONDAZOLIC ACID
4 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
- ottokemi
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberL4900
- Product descriptionLonidamine mitochondrial hexokinase inhibitor
- Packaging5MG
- Price₹11409.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL4900
- Product descriptionLonidamine mitochondrial hexokinase inhibitor
- Packaging25MG
- Price₹50217.18
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number L 3912
- Product descriptionLonidamine
- Packaging5mg
- Price₹39069
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number L 3912
- Product descriptionLonidamine
- Packaging25mg
- Price₹139059
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | L4900 | Lonidamine mitochondrial hexokinase inhibitor | 5MG | ₹11409.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L4900 | Lonidamine mitochondrial hexokinase inhibitor | 25MG | ₹50217.18 | 2022-06-14 | Buy |
| ottokemi | L 3912 | Lonidamine | 5mg | ₹39069 | 2022-05-26 | Buy |
| ottokemi | L 3912 | Lonidamine | 25mg | ₹139059 | 2022-05-26 | Buy |
Properties
Melting point :207-209°C
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :3.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :3.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Lonidamine is a derivative of indazole-3-carboxylic acid. It is a kind of orally administrated small molecule, which can inhibit the glycolysis process through inactivating the hexokinase (the first step in glycolysis). It has been shown that cancer cell primarily generates energy through glycolysis process. Therefore, Lonidamine has been used for the treatment of several kinds of cancers. One special property of Lonidamine is that it seems to enhance aerobic glycolysis in normal cells, but inhibit glycolysis only in cancer cells. In addition, there are also evidences that Lonidamine may increase the occurrence of apoptosis. It has also been shown that Lonidamine is effective in the treatment of benigh prostatic hyperplasia (BPH).Related product price
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