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GSK-3326595

GSK-3326595 Structure
CAS No.
1616392-22-3
Chemical Name:
GSK-3326595
Synonyms
GSK3326595;6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide;EPZ-015938;GSK-3326595,EPZ-015938;EPZ-015938 (GSK3326595);EPZ015938(pemrametostat);Pemrametostat (GSK3326595);EPZ015938; EPZ 015938; EPZ-015938;Pemrametostat, GSK3326595, EPZ015938;6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1
CBNumber:
CB03121890
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.55
MOL File:
1616392-22-3.mol
Modify Date:
2023/6/8 9:03:09
Request For Quotation

GSK-3326595 Properties

Boiling point 760.3±60.0 °C(Predicted)
Density 1.275±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Soluble in DMSO (up to 20 mg/ml).
pka 12.44±0.46(Predicted)
form solid
color Off-white
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

GSK-3326595 Chemical Properties,Uses,Production

Uses

GSK-3326595 is a protein arginine methyltransferase 5(PRMT5) inhibitor under clinical trial.

GSK-3326595 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK-3326595 Suppliers

Global( 92)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Chemtour Biotech Co., Ltd +8617327281506 China 1460 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Suzhou ARTK Medchem Co., Ltd. +8618168183658 China 39009 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
Career Henan Chemica Co 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Chemtour Biotech Co., Ltd 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Suzhou ARTK Medchem Co., Ltd. 58

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EPZ-015938 4-Pyrimidinecarboxamide, 6-[(1-acetyl-4-piperidinyl)amino]-N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]- GSK-3326595,EPZ-015938 EPZ-015938 (GSK3326595) 4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamid 6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1 EPZ015938; 6-[(1-ACETYLPIPERIDIN-4-YL)AMINO]-N-[(2S)-2-HYDROXY-3-(1;2;3;4-TETRAHYDROISOQUINOLIN-2-YL)PROPYL]PYRIMIDINE-4-CARBOXAMID EPZ015938; EPZ 015938; EPZ-015938 EPZ015938(pemrametostat) GSK3326595 6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide 6-[(1-acetyl-4-piperidyl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]pyrimidine-4-carboxamide Pemrametostat, GSK3326595, EPZ015938 Pemrametostat (GSK3326595) 1616392-22-3 API