GSK583

GSK583 Structure
CAS No.
1346547-00-9
Chemical Name:
GSK583
Synonyms
SK583;GSK583;CS-2216;GSK583, >98%;GSK-583;GSK 583;GSK583 >=98% (HPLC);RIP2 kinase inhibitor 583;6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine;6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine;4-Quinolinamine, 6-[(1,1-dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-
CBNumber:
CB63128826
Molecular Formula:
C20H19FN4O2S
Molecular Weight:
398.45
MOL File:
1346547-00-9.mol
Modify Date:
2023/9/4 15:50:00

GSK583 Properties

Boiling point 652.9±55.0 °C(Predicted)
Density 1.402±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Soluble in DMSO (up to at least 25 mg/ml).
form solid
pka 12.59±0.40(Predicted)
color Pale yellow
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

GSK583 Chemical Properties,Uses,Production

Uses

GSK 583, is a selective inhibitor of RIP-like interacting CLARP kinase RIP2 Kinase is a central component of the innate immune system and enables downstream signaling following activation of the pattern recognition receptors NOD1 and NOD2, leading to the production of inflammatory cytokines.

GSK583 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 75)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry

GSK583 Spectrum

GSK583 SK583 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine RIP2 kinase inhibitor 583 CS-2216 GSK583, >98% GSK-583;GSK 583 4-Quinolinamine, 6-[(1,1-dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)- GSK583 >=98% (HPLC) 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine GSK-583,GSK583,RIPK,Inhibitor,Receptor-interacting protein kinases,RIP kinase,GSK 583,inhibit 1346547-00-9